1 / 22

Blue Tongue and Foot and Mouth Disease BWBL Seminar 20.11.12

Blue Tongue and Foot and Mouth Disease BWBL Seminar 20.11.12. David Hucker B.V.Sc. M.A.N.Z.C.V.Sc. Blue Tongue Virus. Transmitted by Midges ( Culicoides spp ) Causes fever, abortion, breathing and circulation problems(hence blue tongue)

ledell
Download Presentation

Blue Tongue and Foot and Mouth Disease BWBL Seminar 20.11.12

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Blue Tongue and Foot and Mouth DiseaseBWBL Seminar 20.11.12 David Hucker B.V.Sc. M.A.N.Z.C.V.Sc.

  2. Blue Tongue Virus • Transmitted by Midges (Culicoides spp) • Causes fever, abortion, breathing and circulation problems(hence blue tongue) • Mortality 0% in accustomed sheep to 90% in susceptible sheep • Are at least 16 strains of BTV

  3. Blue Tongue Virus • Has been in NT sentinel sheep since 1970s? (maybe 1956) • Reservoir of infection in Africa and M. East • Moved into Northern Europe in 2006-8

  4. BTV Movement into Europe 2006-8

  5. BTV Movement into Europe 2008

  6. Concerns • Spread into N Europe • Similar or higher latitude than all of Australia • Some Culiciodes spp in N Europe are here in Vic • Appears to over winter in N Europe then re-emerge • Possibly due to transplacental hibernation????

  7. What about Australia? • Insects eg Culicoides float into Australia periodically from Timor and Papua New Guinea • Can carry arbo viruses eg Blue Tongue, Aino, Akabane and ??Schmallenberg?? • BTV 2 identified in sentinel sheep in NT 2009 • By 2010 BTV 2 was identified in Qld – How did it get there?

  8. Is this a risk for Australia? • Blood from Qld passaged in a sheep at AHL, Geelong 2010 • Sheep severely affected with BTV by day 12 and had to be euthanased • Blood from this sheep used to infect 3 sheep in sentinel flock in NT • All became severely affected and were euthanased Source: nunetherlands.com

  9. Should we be concerned ? • Culicoides spp • In Europe Culicoides imicola was main vehicle for spread • In Australia, Culicoides brevitarsus likely to be main transmitter. • These two species of Culicoides are very similar • Normal biosecurity measures on farm will have little effect on flying insects

  10. What can we do? • Control possibilities • Vaccine – is strain specific and will take 9 months to produce once infection confirmed • Culicoides brevitarsus (suspected to be main transmitter in Australia) reproduces in cattle dung. • Culicoides susceptible to Ivermectin • Therefore may be possibility of controlling vector by treating cattle with ivermectin

  11. Management of BTV • Vaccination • UK • killed vaccine • $2 per head yearly • South Africa • Live attenuated vaccine • Once in a lifetime • But vaccine can be infective • Insect Control • House sheep at night? • Ivermectin???

  12. Foot and Mouth Disease

  13. Foot and Mouth Disease in Australia • Until now - Control by Eradication or Stamp Out • But after UK 2001 Governments wary of adverse publicity

  14. Foot and Mouth Disease • Australia now leaning towards Vaccination • International symposium in Melb in May 2010 • International workshop on FMD outbreak • How would vaccine be used? • When? • What issues may arise? Source: MSD animal health

  15. Foot and Mouth Disease • Vaccination • There are 7 strains of FMD – Vaccine needs to be the right strain • Australia has agreement with Merial UK to supply 500 000 doses of oil adjuvant vaccine (will give +ve blood tests for about 12 months) • Will take about a week to prepare vaccine • This will be enough to cover a small ring vaccination of one outbreak only • Depending on type, more vaccine may be available from UK

  16. Foot and Mouth Disease • Diagnosis • Blood tests look for antibodies = evidence of infection • But both natural infection and vaccination cause antibodies • How can we tell vaccinated from infected animals? • DIVA test = Differentiate between Infected and Vaccinated Animals

  17. Foot and Mouth Disease • Diagnosis by DIVA tests • More highly purified vaccines antibodies can be differentiated using monoclonal and polyclonal antibody reagents – Not good enough for the 2001 UK outbreak but used in 2001 Uruguay outbreak • Recombinant antibody tests developed by CSIRO in 2007 are now better and cheaper

  18. Foot and Mouth Disease • Trade Issues (OIE) • Trade prohibited for 3 months after last case • Extensive surveillance needed to prove this • Only once has this been achieved so usually much longer • Trade prohibited for 3 months after last case or vaccinated animals slaughtered • Extensive surveillance needed to prove this • Trade prohibited for 6 months after last case OR vaccination withdrawal (animals allowed to live) • If using this method need DIVA testing and surveillance

  19. Foot and Mouth Disease • Trade Issues • Outbreak could be expected to last up to 2 years before trade can resume • What do we do with the slaughtered animals? • Can’t export and we can’t eat that many • Effect on stock values? • Will be a real problem!

  20. Foot and Mouth Disease(a tale of two outbreaks) • UK Feb 2001 outbreak was well publicised • Uruguay May 2001 outbreak almost unheard of

  21. Foot and Mouth Disease(a tale of two outbreaks) • Final outcome after eradication Note: Only cattle vaccinated in Uruguay. 24 million doses of vaccine used in Uruguay

  22. Conclusions • Blue Tongue Virus • May be more of a threat to Southern sheep areas than previously thought • Foot and Mouth Virus • Is a risk Australian sheep producers need to be constantly aware of

More Related