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GRAND ROUNDS. Mesenteric and Omental Cyst In An Infant. By Donnie Rose Torres, MD October 3, 2013 ICU Conference Room. To present an approach to a case of abdominal distension in an infant
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GRAND ROUNDS Mesenteric and Omental Cyst In An Infant By Donnie Rose Torres, MDOctober 3, 2013ICU Conference Room
To present an approach to a case of abdominal distension in an infant • To discuss the approach to diagnosis, incidence, management, complications and prognosis of patients with mesenteric and omental cyst • To present hemangiolymphangioma as a histological finding for mesenteric and omental cyst Objectives
RA DG, 1-month old female from Calbayog, Samar admitted from AFP Medical Center coordinated transfer to our institution last June 29, 2013 Chief Complaint: ABDOMINAL DISTENSION Patient’s Data
General:(-) weight loss Skin: (-) excessive dryness ENT: (-)epistaxis, (-)excessive salivation , (-) eye and ear discharge Neck: (-)limitation of movement Respiratory: (-)cough, (-) colds, (-) difficulty of breathing Review Of Systems
Gastrointestinal: (-) vomiting, regular bowel movement, (-) constipation, (-) hematemesis, (-) melena, (-) hematochezia, (-) acholic stools Endocrine: (-)polyuria, (-) polydipsia Genitourinary: (-)discharge, (-) genital rashes, (-) hematuria Musculoskeletal: (-)limitation of movement Nervous system: (-) irritability, (-) changes in activity Review Of Systems
(+) history of DM – paternal side (+) history of Hypertension – maternal side (-) history of Asthma, Malignancy, TB, Renal and Hepatic diseases on both sides 26 housewife 21 soldier Family History
(+) BCG • (+) Hepatitis B 1st dose - given upon birth Immunization History
Exclusively breastfed Nutritional History
No history of blood transfusion • No allergies to drugs Past Medical History
lives with parents and 3 other relatives • 2-storey, 3-bedroom house • owned by their family • (-) exposure to smoking • (-) exposure to chronic cough • use tap water for consumption • garbage collected thrice a week Personal and Social History
General Survey: awake, not irritable, active Vital signs: BP: 80/50 Wt: 5.6 kgs (z score 2) BSA: 0.28 CR: 130 bpm Lt: 53 cm (z score 0) RR 34 cpm HC: 38 cm (z score 0) T: 36.7 oCCC: 35 cm AC: 44cm umbilical level, 46cm widest diameter Skin: jaundice from face to chest, warm, moist skin HEENT: open and flat anterior and posterior fontanelles, no molding, (+) erythematous maculopapular rashes on the face,anicteric sclerae, nonsunken eyeballs, pink palpebral conjunctiva, no nasoaural deformities and discharges, moist lips, no cleft lip, no cleft palate, no neck masses, no cervical lymphadenopathies Physical Examination
Chest and lungs: no gross chest deformities, symmetric chest expansion, good air entry, clear breath sounds, no retractions Cardiovascular: adynamic precordium, no heaves nor thrills, regular rate and rhythm, distinct heart sounds, apex beat at 4th intercostals space mid-axillary line, no murmurs Genitalia:grossly female-looking genitalia Anus:patent anal opening Spine:straight spinal column, no spinal masses, no sacral dimpling, no tufts of hair Extremities:no polydactyly, no other deformities, no edema, full and equalpulses, good capillary refill time Physical Examination
Abdomen: • distended, AC – 44 cm umbilical level, 46 cm widest diameter • (+) prominent abdominal veins • normoactivebowel sounds • Tympanitic • soft • (-) hepato-splenomegaly, • (+) 5 x 6 cm, solid, ill-defined mass palpated midline Physical Examination
awake, active CN I: not assessed CN II:(+) dazzle CN II , III:pupils 2-3 mm equally reactive to light CN III, IV, VI:full and equal EOM CN V: not assessed CN VII:no facial asymmetry CN VIII:not assessed CN IX, X: good gag reflex CN XI: not assessed CN XII: tongue at the midline, no fasciculation Motor:Normal muscle bulk; Normal muscle tone; No fasciculation Sensory: withdraws to pain stimuli (+) Babinski, bilateral, No clonus Signs of Meningeal Irritation: (-)nuchal rigidity, Brudzinski sign: negative, Kernig sign: negative Reflexes:(+) rooting, palmar, Moro Neurologic Examination
Ascites vsPelvo-abdominal Mass, Pobably: 1. Ovarian cyst 2. Germ cell tumor 3. Mesenteric and Omental cyst No wasting, no stunting Working Diagnosis
Abdominal distension hepatic ASCITES renal cardiac Approach to the Diagnosis Pregnancy/obesity tumors
miscellaneous trauma OLDER CHILDREN ASCITES neoplasia infection Hepatocellular disease Gynecologic or GIT abN Approach to the Diagnosis
Spontaneous perforation of the bile duct biliary Perforation of choledocal cyst NEONATAL ASCITES urinary Complex urinary anomalies Perforation of bladder or ureteral tract chylous Approach to the Diagnosis Idiopathic Congenital lymphatic Abn Hernia Intususception Neoplasm External compression of lymphatics
Pertinent - • Feeding intolerance • Rare • Direct hyperbilirubinemia • UTZ findings • Pertinent + • Age group (< 3 months) • Mild jaundice • Abdominal distension biliary • Pertinent + • Abdominal distension NEONATAL ASCITES urinary • Pertinent - • Male predominance • Prenatal UTZ • oligohyramnios • Metabolic acidosis • Elevated BUN/Crea • Electrolyte ABN chylous Miscellaneous Cardiac Infection Approach to the Diagnosis • Pertinent + • Congenital • Abdominal distension • UTZ and CT Scan findings • Pertinent - • Feeding intolerance • Male predominance
Idiopathic CHYLOUS ASCITES Mesenteric/Omental Cyst Congenital lymphatic Abn Hernia Ovarian Mass External compression of lymphatics Intususception Approach to the Diagnosis Tumors/Neoplasm Germ cell tumors hepatoblastoma
Assessment of Abdominal Mass Ch 78, by RH Sills Practical Algorithms in Hematology and Oncology
Assessment of Abdominal Mass Ch 78, by RH Sills Practical Algorithms in Hematology and Oncology
Assessment of a Pelvic Mass Ch 80, by RH Sills Practical Algorithms in Hematology and Oncology
Ascites vsPelvo-abdominal Mass, Pobably: 1. Ovarian cyst 2. Germ cell tumor 3. Mesenteric and Omental cyst No wasting, no stunting Working Diagnosis
1stHosp day • Jaundice • Distended abdomen • Prominent veins • Soft • No organomegaly • Ill defined mass • The rest of PE and Neuro exam NORMAL LABS Course In the Wards
1stHosp day • Heplock • DBF • Gyne, Hema and Surgery • HEMA: • A> Pelvo-abdominal Mass prob ovarian in origin, r/o GCT • Hydration • Aluminum Hydroxide • Monitoring of Tumor Markers • JAUNDICE LDH BHCG AFP • TUMOR MARKERS • GYNE/SURG: • A> Pelvo-abdominal Mass prob ONG • Ex-Lap Course In the Wards
2ndHosp day • WARDS • Gr 2/6 HS murmur 2nd ICS LPSB • IVF mtn rate 2 d echo: PFO Salbutamol neb IVF mtn rate • Hyperkalemia • Hypercalcemia • Rpt LABS • Normokalemia • Hypercalcemia • Normal U/A • Uncompensated Metabolic acidosis • A> T/C TumorLysis Syndrome, Hypercalcemia of Malignancy Hydration 2L/BSA Course In the Wards
2ndHosp day • Hyperkalemia • Hyperphosphatemia • Hyperuricemia • Hyperuricosuria • Hypocalcemia • Lactic acidosis • TUMOR LYSIS SYNDROME • Vs Pre-treatment spontaneous TLS • Treatment • Targeted to specific metabolic disorder • Hyperkalemia – pushes K back intracellularly • Hyperphosphatemia – hydration, AlOH • Acidosis – Hydration, NaHCO3 • Laboratory TLS • Cairo-Bishop definition • Clinical TLS Course In the Wards
2ndHosp day • HYPERCALCEMIA • OF MALIGNANCY • Treatment • Targeted to underlying cause • Hydration – decreased Ca through dilution, incraeses renal Ca clearance • Forced diuresis – increased Ca excretion, avoid volume overload, increase Ca reabsorption • Bisphophonates – inhibit osteoclast activity Course In the Wards
6th to 9th Hosp day • Pre-op Conference • Pre-op Labs Course In the Wards
Ascites vsPelvo-abdominal Mass, Pobably: 1. Ovarian cyst 2. Germ cell tumor 3. Mesenteric and Omental cyst No wasting, no stunting Working Diagnosis
10thHosp day • Marsupialization of the mesenteric cyst • Exploratory Laparotomy • Intra-op findings: • Mesenteric cyst occupying almost all of the small intestine mesentery extending to the retroperitoneal space • Intra-op findings: • 5 x 7 cm omental cyst with chylous contents • Milky ascites Course In the Wards
Mesenteric and OmentalCyst S/P Excision of Cyst and Marsupialization of Mesenteric Cyst (7/8/13), Chylous ascites No wasting, No stunting Working Diagnosis