NOVEL APPROACHES FOR BIOTECHNOLOGY TRAINING AT COMMUNITY COLLEGES

1. NOVEL APPROACHES FOR BIOTECHNOLOGY TRAINING AT COMMUNITY COLLEGES Linda R. Rehfuss May 6, 2007 Boston, MA

2. Biotechnology Education • Biotechnology programs offered since Fall 2002 • 3 Biotechnology programs • A.S., designed for transfer • A.A.S., career track • A.A.S. in Biotechnology, Nanobiotechnology option (4th semester capstone at Penn State) • 5 Biotechnology-specific courses developed

3. MCCC Biotech Students

4. Advanced Technology Center (ATC)

5. New Lab in ATC

6. MCCC Biotech Program • 5 Biotech-specific courses: • Introduction to Biotechnology - recombinant DNA, drug discovery process, patents • Basic Techniques for Biotechnology - pH, micropipettors, UV spec • Biotechnology Research - recombinant DNA techniques, PCR, genetics • Biotechnology Manufacturing - GMP regulations, QA and QC • Biotechnology Internship - fieldexperience

7. 2+2+2 Partners • Technical High Schools: • North Montco Technical Career Center • Center for Technical Studies of Mont. Cty. • Community Colleges: • Montgomery County Community College • Bucks County Community College • Community College of Philadelphia • 4 Year Colleges and Universities: • Thomas Jefferson University • Cabrini College • Penn State – Abington College

8. Activities • Students from Vo-tech schools • summer camps • Teacher training programs • Workforce Investment Board (WIB)

9. Education Collaborators • Kevin Lampe, Assistant Professor of Biotechnology, MCCC • Christopher Harendza, Ph.D., Professor of Biology, MCCC • Evon Martins, Ph.D., Assistant Professor of Chemistry • Laura McAtee, Ph.D., Instructor of Chemistry, MCCC • Lori Dodson, Ph.D., Biotechnology Instructor, North Montco Technical Career Center, Lansdale, PA • Rich Coletta, Biotechnology Instructor and Program Development, Center for Technical Studies of Montgomery County, Plymouth Meeting, PA • Esther E. Biswas-Fiss, Ph.D., Associate Professor and Program Director in Biotechnology, Thomas Jefferson University, Philadelphia, PA • Sheryl L. Fuller-Espie, Ph.D., DIC, Associate Professor of Biology, Science Department Chair, Cabrini College, Radnor, PA • Melanie Lenahan, Ph.D., Assistant Professor and Program Director in Biotechnology, Raritan Valley Community College, Somerville, NJ • Randy Libros, Associate Professor of Physics, Community College of Philadelphia, Philadelphia, PA • Laura Anne Roselli, Instructor and Program Consultant for Biotechnology, Burlington County College, Mt. Laurel, NJ

10. Industry Collaborators • Thomas Hartnett, P.E., Sr. Director of Engineering, Pharmaceutical Sourcing Group of the Americas, Johnson and Johnson Family of Companies, Bridgewater, NJ • Joseph P. Lingle, P.E., Director, Facilities Operations, GlaxoSmithKline, King of Prussia, PA • Thomas B. Lavoie, Ph.D., Section Head, Protein Biochemistry, PBL Biomedical Laboratories, Piscataway, NJ • Peter Lowry, Vice President, Operations, The Immune Response Corporation, King of Prussia, PA • Thom Moll, Manager, Fluids Manufacturing Area, Merck and Co., Inc., West Point, PA • Cynthia Sarnoski, Ph.D. Sr. Vice President, Global Quality Assurance, Wyeth, Collegeville PA • Richard P. Schwartz Jr., Ph.D., President, CV Ventures, LLC, Blue Bell, PA • Dr. Carol Adukaitis, 2+2+2 WLG Program Manager, PA State System of Higher Education, Harrisburg, PA • Life Science Career Alliance, Philadelphia, PA • Collegiate Consortium

11. Partnership with Rohm and Haas • R & H Chemical company with Healthcare division • Developed polymeric separation media • Trying to extend platform technologies • Want to use media for purification of high molecular weight drugs • Partner with MCCC in the ATC for project

12. R & H –MCCC Partnership • Benefit to Company: • Polymers tested in biological systems (R & H doesn’t have cell culture capabilities) • Extend product capability • Materials produced and tested in R & H facilities • Trained students for internships and future employees

13. R & H –MCCC Partnership • Benefit to College: • Well trained students – college paid “internship” • ATC use • Students versed in a variety of techniques and equipment • Students provided on-site training at R & H as well in analytical techniques • Growing the reach of NBC2

14. Merck-MCCC Partnership • Vaccine division collaboration • Aseptic awareness course • 1 week for new hires; 1-2 day for incumbent workers • Attributes sought: gowning, behavioral practices, skills used in aseptic manufacturing • ATC collaboration as well

15. Merck-MCCC Partnership • Students may participate – compliments their didactic and in class laboratory instruction • Extends company-college-community reach • Provided through non-credit opportunities at the College • Pilot with Merck could be extended to other companies

16. Teacher Training Institute • STEM disciplines at College: Biotechnology, Biology, Chemistry, Physics, Engineering, Math • Grades 7-12 and Community College teachers and faculty • Teachers participate in R&H and Merck projects – help them prepare their students

17. Funding for Projects offered at the College • NSF (preliminary proposals and current grant) • DOL • Company (R &H, Merck) • Private investors • State funds • ANYONE WITH OTHER FUNDING IDEAS?

18. Where Are MCCC Interns & Grads?

19. 10 Critical Biomanufacturing Jobs for NBC2 • Process Development Associate • Validation Specialist • Manufacturing Technician - Upstream • Manufacturing Technician - Downstream • Instrumentation/Calibration Technician • Chemistry QC Technician • Microbiology QC Technician • Environmental Health & Safety Technician • QA Documentation Coordinator • Facilities Technician

20. MCCC Contact Information Linda Rehfuss, Ph.D. Montgomery County Community College 340 DeKalb Pike Blue Bell, PA 19422 lrehfuss@mc3.edu 215-641-6643 http://faculty.mc3.edu/lrehfuss/lrehfuss.htm Kevin Lampe, M.S. Assistant Professor of Biotechnology 215-641-6499 klampe@mc3.edu