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D ’ après Astrup et al., Int J Obes 2011;doi/10.1038/ijo.2011.158

Variation du poids entre l ’ inclusion et 2 ans de suivi. Orlistat 120 mg 3 x/j Placebo. Liraglutide 1,2 mg Liraglutide 1,8 mg. Liraglutide 2,4 mg Liraglutide 3,0 mg. 2. n = 356. n = 561. n = 526. n = 268. 0.

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D ’ après Astrup et al., Int J Obes 2011;doi/10.1038/ijo.2011.158

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  1. Variation du poids entre l’inclusion et 2 ans de suivi Orlistat 120 mg 3 x/j Placebo Liraglutide 1,2 mg Liraglutide 1,8 mg Liraglutide 2,4 mg Liraglutide 3,0 mg 2 n = 356 n = 561 n = 526 n = 268 0 Tous les patients sous liraglutide/placebo ont reçu du liraglutide 2,4 mg à partir de S52, puis 3 mg entre S70 et S96 -2 -4 Perte de poids moyenne(kg) À partir du screening -6 -6,7 kg -8 -8,8 kg -9,4 kg -9,4 kg -9,9 kg -10,3 kg -10 Randomisation -12 Screening -14 104 0 96 -4 68 20 52 Semaines D’après Astrup et al., Int J Obes 2011;doi/10.1038/ijo.2011.158

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