Doxorubicin Moa
Doxorubicin, often regarded by the trade name “adriamycin”, is a member of the anthracycline compounds derived from Streptomyces peucetius var. caesius in the 1960s. These compounds were given the name doxorubicin or daunorubicin. Doxorubicin and its derivatives, function by DNA helix intercalation, topoisomerase poisoning, free radical generation…, are still regarded as some of the most impactful chemotherapeutic antitumor agents.
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