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Genes and Function: The Rewriting of our <br />Textbooks of Pathology. Presented By David Hafler at 2014 ASCO Annual Meeting. Slide 2. Presented By David Hafler at 2014 ASCO Annual Meeting. Slide 3. Presented By David Hafler at 2014 ASCO Annual Meeting. Slide 4.
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Genes and Function: The Rewriting of our <br />Textbooks of Pathology Presented By David Hafler at 2014 ASCO Annual Meeting
Slide 2 Presented By David Hafler at 2014 ASCO Annual Meeting
Slide 3 Presented By David Hafler at 2014 ASCO Annual Meeting
Slide 4 Presented By David Hafler at 2014 ASCO Annual Meeting
Slide 5 Presented By David Hafler at 2014 ASCO Annual Meeting
Slide 6 Presented By David Hafler at 2014 ASCO Annual Meeting
Slide 7 Presented By David Hafler at 2014 ASCO Annual Meeting
Slide 8 Presented By David Hafler at 2014 ASCO Annual Meeting
Slide 9 Presented By David Hafler at 2014 ASCO Annual Meeting
Slide 10 Presented By David Hafler at 2014 ASCO Annual Meeting
Slide 11 Presented By David Hafler at 2014 ASCO Annual Meeting
Slide 12 Presented By David Hafler at 2014 ASCO Annual Meeting
Slide 13 Presented By David Hafler at 2014 ASCO Annual Meeting
Slide 14 Presented By David Hafler at 2014 ASCO Annual Meeting
Slide 15 Presented By David Hafler at 2014 ASCO Annual Meeting
Glioblastoma multiforme Presented By David Hafler at 2014 ASCO Annual Meeting
Treatments Presented By David Hafler at 2014 ASCO Annual Meeting
WHO Classification Presented By David Hafler at 2014 ASCO Annual Meeting
Slide 19 Presented By David Hafler at 2014 ASCO Annual Meeting
Slide 20 Presented By David Hafler at 2014 ASCO Annual Meeting
PD-1 Expression CD4 T effectors in on Glioblastoma Presented By David Hafler at 2014 ASCO Annual Meeting
Slide 22 Presented By David Hafler at 2014 ASCO Annual Meeting
Slide 23 Presented By David Hafler at 2014 ASCO Annual Meeting
Slide 24 Presented By David Hafler at 2014 ASCO Annual Meeting
Slide 25 Presented By David Hafler at 2014 ASCO Annual Meeting
Patient survival linked to Tumor-associated Tregs Presented By David Hafler at 2014 ASCO Annual Meeting
Increase numbers of regulatory T Cells in Glioblastoma Presented By David Hafler at 2014 ASCO Annual Meeting
Tregs and CD4 T effector cells in glioblastoma are Tim3+PD-1+ Presented By David Hafler at 2014 ASCO Annual Meeting
Slide 29 Presented By David Hafler at 2014 ASCO Annual Meeting
PD-1+Tim3+ Tregs restricted to grade 4 glioblastoma Presented By David Hafler at 2014 ASCO Annual Meeting
Absence of Tim3+PD-1+ Tregs in the blood of healthy controls Presented By David Hafler at 2014 ASCO Annual Meeting
Slide 32 Presented By David Hafler at 2014 ASCO Annual Meeting
Slide 33 Presented By David Hafler at 2014 ASCO Annual Meeting
Slide 34 Presented By David Hafler at 2014 ASCO Annual Meeting
Slide 35 Presented By David Hafler at 2014 ASCO Annual Meeting
Blocking monoclonal antibodies increase CD4 T effector proliferation but not Treg suppression Presented By David Hafler at 2014 ASCO Annual Meeting
Slide 37 Presented By David Hafler at 2014 ASCO Annual Meeting
Impaired suppression by GBM-Treg and proliferative response by GBM-Teff Presented By David Hafler at 2014 ASCO Annual Meeting
PD-1+Tim3+ Tregs have decreased suppressor function Presented By David Hafler at 2014 ASCO Annual Meeting
PD-1+ CD4 effector cells and Tregs have shortened telomeres Presented By David Hafler at 2014 ASCO Annual Meeting
Slide 41 Presented By David Hafler at 2014 ASCO Annual Meeting
Slide 42 Presented By David Hafler at 2014 ASCO Annual Meeting
Slide 43 Presented By David Hafler at 2014 ASCO Annual Meeting