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Researchers Rutnumnoi Thanachat 52460390 Ridamrong Waraporn 52460888 Advisors

Prevalence of Helicobacter pylori infection in chronic dyspeptic patients with peptic ulcer in Naresuan University Hospital. Researchers Rutnumnoi Thanachat 52460390 Ridamrong Waraporn 52460888 Advisors Jiratwang Manatchanok , MD. Lertkajornsin Suwit , MD. Background.

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Researchers Rutnumnoi Thanachat 52460390 Ridamrong Waraporn 52460888 Advisors

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  1. Prevalence of Helicobacter pylori infection in chronic dyspeptic patients with peptic ulcer in Naresuan University Hospital Researchers RutnumnoiThanachat 52460390 RidamrongWaraporn 52460888 Advisors JiratwangManatchanok, MD. LertkajornsinSuwit, MD.

  2. Background Helicobacter pylori • Gram-negative, curved S-shaped, microaerophilic bacterium • Most common cause of gastritis, peptic and duodenal ulcers and gastric adenocarcinoma

  3. Objectives • To find out the prevalence of H. pylori infection in chronic dyspeptic patients with peptic ulcer. • To explore the relationship between the characteristics of ulcer and the H. pylori infection.

  4. Method • A cross-sectional descriptive study was performed by collecting data in EGD clinic, Naresuan University hospital during October 2004 to August 2012. • The diagnosis of Helicobacter pylori infection was done by Rapid Urease Test and Histological examination. • Stataversion12 was used to conclude the information.

  5. Method • Inclusion criteria • Patients with dyspepsia which had been diagnosed by a specialist. • Patients who underwent upper gastrointestinal endoscopy clinic at Naresuan University Hospital with indication of Dyspepsia. • Patients with Helicobacter pylori infection results diagnosed by Rapid Urease Test and / or Histological Examination.

  6. Method • Exclusion criteria • Patients with other indications for upper gastrointestinal endoscopy beyond dyspepsia. • Patients who were diagnosed as Helicobacter pylori infection by both Rapid Urease Test and Histological Examination.

  7. Method Chronic dyspeptic patients who underwent the EGD at NUH during Oct 2004 to Aug 2012 Inclusion criteria Exclusion criteria 53 patients

  8. Results Table 1 : Demographic data of chronic dyspeptic patients with peptic ulcer who underwent EGD at NUH between Oct 2004 – Aug 2012.

  9. Results Bar graph 1 : Endoscopic findings of Chronic dyspeptic patients with peptic ulcer who underwent EGD at NUH between Oct 2004 – Aug 2012. 90.57% 7.55% 1.88%

  10. Results Bar graph 2 : Rapid urease test results for detection of Helicobacter pylori infection in Chronic dyspeptic patients with peptic ulcer who underwent EGD at NUH between Oct 2004 – Aug 2012. 66.04% 33.96%

  11. Results : Bar graph 3 Bar graph 3 : Histological examination results for detection of Helicobacter pylori infection in Chronic dyspeptic patients with peptic ulcer who underwent EGD at NUH between Oct 2004 – Aug 2012. 66.67% 33.33%

  12. Results Table 2 : The relationship between Rapid urease test results for detection of Helicobacter pylori infection in Chronic dyspeptic patients who underwent EGD at NUH between Oct 2004 – Aug 2012. and endoscopic findings

  13. Results Table 3 : The relationship between Histological examination results for detection of Helicobacter pylori infection in Chronic dyspeptic patients who underwent EGD at NUH between Oct 2004 – Aug 2012. and endoscopic findings

  14. Results Table 4 : The prevalence of Helicobacter pylori infection in patients with Chronic dyspeptic patients with peptic ulcer who underwent the EGD at NUH between October 2004 - August 2012. The prevalence was 37.74% (20 of 53 patients)

  15. Conclusion • The prevalence of H. pylori infection was still high in the chronic dyspeptic patients with peptic ulcer. • This may relate to GU, DU and combined GU and DU. • There was no significant difference in relationship between endoscopic findings and Helicobacter pylori infection which detected by Rapid urease test or Histological examination.

  16. THANK YOU

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