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With Semantic Analysis from Noun Phrases to SNOMED CT and Classification Codes Hans Rudolf Straub Semfinder AG, Switzerland. Reality Instances. Free Text Terminologies Classifications Groups / Statistics. Information Content per Case (in Bits ). Reality Instances.
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With Semantic Analysis from Noun Phrases to SNOMED CT and Classification Codes Hans Rudolf Straub Semfinder AG, Switzerland
Reality Instances Free Text Terminologies Classifications Groups / Statistics . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
InformationContent per Case (in Bits) Reality Instances Free Text Terminologies Classifications Groups / Statistics . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . (512k)19100 . . . (16k)1428 (512)9
Reality Instances Free Text Terminologies Classifications Groups / Statistics . . . . . . . • Information • Reduction is • Enormous- Inevitable- Ubiquitous • Necessary . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Reality Instances . . . . . . . • Information • Reduction is • Enormous- Inevitable- Ubiquitous • Necessary . . . . . . . . . Simplification is necessary and useful . . . . . . . . . . . . . . . . . . . . . . . . . . Overviews Statistics Comparisons Basis for Actions
Reality Instances . . . . . . . • Information • Reduction is • Enormous- Inevitable- Ubiquitous • Necessary • Deducible? . . . . . . . . . Simplification is necessary and useful . . . . . . . . . . . . . . . . . . . . . . . . . . Overviews Statistics Comparisons Basis for Actions
Reality Instances . . . . . . . Deducible? . . . . . . . . . Simplification is necessary and useful . . . . . . . . . . . . . . . . . . . . . . . . . . Overviews Statistics Comparisons Basis for Actions = Hierarchy?
When is a Hierarchy a True Hierarchy? 1) Disjunctivity Species Barrier2) Unidirectionality Time Arrow Deducible! = Hierarchy
Forms any Ontology of Diseases a True Hierarchy? 1) Disjunctivity Species Barrier for Diseases? 2) Unidirectionality Natural Time Arrow? Deducible?
Problems with Hierarchies for Diseases 1) Inherent Multidimensionality (Combinatorial Explosion) 2) Sum/Summands Problem
ICD-10: Several Dimensions in 1 Hierarchy organic complications causes causes I10 primary hypertension I11 hypertensive cardiopathy I12 hypertensive nephropathy I13 hypertensive cardiop. + nephrop. I15 secondary hypertension 3-digits I10 – I15 arterial hypertension group
ICD-10: Several Dimensions in 1 Hierarchy 5-digits I11.00without crisis I11.01with crisis I15.20without crisis I15.21with crisis ... ... ... I11.0with cardiac insufficiency I11.9without card. Insuff. I12.0with renal insufficiency I12.9without ren. insuff. .. H .. N I13.2 H+N .. - 4-digits I15.0reno- vasc. I15.1reno- paren. I15.2 endo- crinous I10.0benign I10.1malignant I10 primary hypertension I11 hypertensive cardiopathy I12 hypertensive nephropathy I13 hypertensive cardiop. + nephrop. I15 secondary hypertension 3-digits I10 – I15 arterial hypertension group
2 Hierarchies Pathogenes Bacterium Pathogene Virus Organs 2 Choices 2 Degrees of freedom Resp. Organ Alimentary Organ Organ Representation of 2 Axes (= 2 Hierarchies) Germ Bacterium Germ Virus Organ 2 Choices 2 Degrees of Freedom Respiratory Organ Digestive Organ Organ = 2 Semantic Axes = 2Degrees of Freedom
12 Hierarchies Germ Certainty Localisation Bakterium Progression Germ Virus Organ Respiratory Organ Digestive Organ Organ 12 Hierarchies cannot be Represented Simultaneously
Encapsulated Axes Pathogenesis Localisation Organ Certainty Root Focus Pathology Focus e.g. Fractur 29 Axes (8 Active)
Concept Molecule StructuredRelationship Group (Postcoordinated)
Sum/Summands Problem Diagnosis of its Own I11.0with cardiac insufficiency I11.9without card. Insuff. I12.0with renal insufficiency I12.9without ren. insuff. .. H .. N I13.2 H+N .. - 4-digits I15.0reno- vasc. I15.1reno- paren. I15.2 endo- crinous I10.0benign I10.1malignant I10 primary hypertension I11 hypertensive cardiopathy I12 hypertensive nephropathy I13 hypertensive cardiop. + nephrop. I15 secondary hypertension 3-digits I10 – I15 arterial hypertension group Attribute of a Diagnosis
Sum/Summands Problem • Autom. Included? • Additional Item? • Sequence? Diagnosis of its Own I50.00 – I50.19 I11.0with cardiac insufficiency I11.9without card. Insuff. I12.0with renal insufficiency I12.9without ren. insuff. .. H .. N I13.2 H+N .. - 4-digits I15.0reno- vasc. I15.1reno- paren. I15.2 endo- crinous I10.0benign I10.1malignant I10 primary hypertension I11 hypertensive cardiopathy I12 hypertensive nephropathy I13 hypertensive cardiop. + nephrop. I15 secondary hypertension 3-digits I10 – I15 arterial hypertension group
Sum/Summands Problem Very Frequent! Diagnosis of its Own I11.0with cardiac insufficiency I11.9without card. Insuff. I12.0with renal insufficiency I12.9without ren. insuff. .. H .. N I13.2 H+N .. - 4-digits I15.0reno- vasc. I15.1reno- paren. I15.2 endo- crinous I10.0benign I10.1malignant I10 primary hypertension I11 hypertensive cardiopathy I12 hypertensive nephropathy I13 hypertensive cardiop. + nephrop. I15 secondary hypertension 3-digits I10 – I15 arterial hypertension group
Sum/Summands Problem Severel Diseases can Coexist and Interrelate in the Same Patient Which of them Defines the Medical Case? Is there a "Hat" Disease? Classification
Sum/Summands Problem + = + = I10 N28.9 I12 Give Sum
Sum/Summands Problem + = + = I12 N19 N19 + I12 Give Summands
Sum/Summands Problem I12 Hypertensive renal diseaseIncludes: any condition in N18.- (renal failure) … … with any condition in I10 arteriosclerosis of kidney, …Excludes: secondary hypertension (I15.-)I12.0 Hypertensive renal disease with renal failure hypertensive renal failureI12.1 Hypertens. renal disease without renal failure hypertensive renal disease NOS I12 Hypertensive renal diseaseIncludes: any condition in N18.- (renal failure) … … with any condition in I10 arteriosclerosis of kidney, …Excludes: secondary hypertension (I15.-)I12.0 Hypertensive renal disease with renal failure hypertensive renal failureI12.1 Hypertens. renal disease without renal failure hypertensive renal disease NOS I12 Hypertensive renal diseaseIncludes: any condition in N18.- (renal failure) … … with any condition in I10 arteriosclerosis of kidney, …Excludes: secondary hypertension (I15.-)I12.0 Hypertensive renal disease with renal failure hypertensive renal failureI12.1 Hypertens. renal disease without renal failure hypertensive renal disease NOS
Which Summand is Stronger? Fine Granularity (Summands) Deductionspossible? Coarse Granularity (Sum) Diagnoses Terminologies Classifications Classification Funnel (=Hierarchy?)
Which Summand is Stronger? + hypertension nephropathy Summands Classification Funnel
Which Summand is Stronger? + hypertension nephropathy Summands diabetic Nethie athero- Nepthie Sum with Full Information hypertensive nephropathy Classification Funnel
Which Summand is Stronger? + hypertension nephropathy Summands diabetic Nethie athero- Nepthie Sum with Full Information hypertensive nephropathy Sum with Reduced Information nephropathy Classification Funnel N
Which Summand is Stronger? + hypertension nephropathy Summands Hypertonie mit Kardiopathie Hypertonie mit Kardiopathie Sum with Full Information hypertension with nephropathy Sum with Reduced Information Classification Funnel
Which Summand is Stronger? + hypertension nephropathy Summands Hypertonie mit Kardiopathie Hypertonie mit Kardiopathie Sum with Full Information hypertension with nephropathy Sum with Reduced Information hypertension Classification Funnel I
Which Summand is Stronger? + hypertension nephropathy Summands diabetic Nethie Hypertonie mit Kardiopathie Hypertonie mit Kardiopathie athero- Nepthie Sum with Full Information hypertension with nephropathy hypertensive nephropathy Sum with Reduced Information hypertension nephropathy Classification Funnel I N Disjunction
Sum/Summands = Normal part_of Relation? Finger part_of Hand Never on Same Level - Natural Hierarchy Hypertension part_of (Hypertensive) Cardiopathy Possibly on Same Level! - Hypertension Can Stand Alone - No Natural Hierarchy
Sum/Summands = Normal part_of Relation? Finger part_of Hand Never on Same Level - Natural Hierarchy Hypertension part_of (Hypertensive) Cardiopathy Possibly on Same Level! - Hypertension Can Stand Alone - No Natural Hierarchy
Sum/Summands = Normal part_of Relation? mandatory part_of contingent part_of Finger part_of Hand (Always) Finger without Hand (Not Naturally Possible) Hypertension part_of Hypert. Cardiopathy (Sometimes) Hypertension withoutHypert. Cardiopathy (Well Possible)
Sum/Summands = Normal part_of Relation? mandatory part_of contingent part_of hand palm ... thumb deductions possible hypertensive cardiopathy hypertension cardiopathy deductions NOT possible
The sum/summands problem is frequent - duodenal ulcer with gastrointestinal bleeding - diabetes with complications: - diabetic nephropathy - diabetic foot - cardiac lung oedema (= symptom cardiac insufficiency) - cerebral aneurysm with subarachnoidal bleeding and coma- monteggia-fracture (= fracture of ulna und luxation of radius) - Weber fracture (tibia + fibula + ligaments) - unhappy triad (meniscus + 2 ligaments) - appendicitis with perforation and peritonitis
Reality Instances Sum/Summands Problem Free Text Terminologies Classifications Groups / Statistics . . . . . . . . . . . . . . . . . . . . . . . . . . . . Many Points . . . . . . . . . . . . . . One Point Simplification is Intended!
Reality Instances Free Text Terminologies Classifications Groups / Statistics . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Severel Classifications of One Case are Possible . . . . . .
From Noun Phrases to Terms and ICD-Codes Automated Coding System Free TextDiagnoses Structured Representationof Semantics ICD-10Codes (In Daily Routine in 180 Hospitals)
From Noun Phrases to Terms and ICD-Codes Automated Coding System Free TextDiagnoses Understanding Texts Structured Representationof Semantics Understanding Codesand Coding Guidelines ICD-10Codes (In Daily Routine in 180 Hospitals)
From Noun Phrases to Terms and ICD-Codes Automated Coding System Free TextDiagnoses Completion Queries Understanding Texts Structured Representationof Semantics Understanding Codesand Coding Guidelines ICD-10Codes (In Daily Routine in 180 Hospitals)
From Noun Phrases to Terms and ICD-Codes Automated Coding System Free TextDiagnoses Completion Queries Understanding Texts Structured Representationof Semantics Understanding Codesand Coding Guidelines ICD-10Codes (In Daily Routine in 180 Hospitals)
Are 2 Systems of Data Entry Necessary? SNOMED CT Automated Coding System Free TextDiagnoses Completion Queries Understanding Texts Structured Representationof Semantics StandardTerms StandardTerms Data Exchange Understanding Codesand Coding Guidelines ICD-10Codes ICD-10 Coding will continue
Are 2 Systems of Data Entry Necessary? SNOMED CT Automated Coding System Free TextDiagnoses Completion Queries Understanding Texts Structured Representationof Semantics StandardTerms StandardTerms Free Data Exchange Understanding Codesand Coding Guidelines ICD-10Codes ICD-10 Coding will continue
From Noun Phrases to Terms and ICD-Codes SNOMED CT Automated Coding System Free TextDiagnoses Completion Queries Understanding Texts Structured Representationof Semantics StandardTerms StandardTerms Free Data Exchange Understanding Codesand Coding Guidelines ICD-10Codes Fixed Standard for Data Exchange Open Method
Summary A description of a coarser granularity cannot automatically be obtained from a description of finer granularity. Diagnoses resist to be arranged in form of a hierarchy due to the inherent multidimensionality and to the sum/summands-problem. Simplifying, grouping and classification of medical diagnosis will always be necessary in practice. When automatically assigning ICD-10 codes to medical cases, their SNOMED clinical terms can be assigned simultaneously.