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Understanding Hemophilia: Genetics of the F8C Gene

Delve into the correlation between hemophilia and defects in the F8C gene on the X chromosome. Learn about inheritance patterns and the challenges faced by those lacking a clotting factor. Explore the famous pedigree of hemophiliacs and carriers in the Russian Royal Family.

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Understanding Hemophilia: Genetics of the F8C Gene

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Presentation Transcript

  1. Hemophilia Genetics of the F8C Gene

  2. F8C Gene • Hemophilia is correlated to defects in the F8C gene. • The F8C gene is found on the X chromosome

  3. Inheritance • Hemophilia is an X-linked recessive disorder that affects one in 10,000 males and very few females • Since females have two X chromosomes, they are often carriers of the gene

  4. Hemophilia Persons who inherit the F8C gene lack a clotting factor to prevent bleeding Even simple cuts may be a serious problem for these people

  5. Famous Pedigree of Hemophiliacs & Carriers

  6. Russian Royal Family

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