Adult Immunization 2010 MMR Vaccine Segment

1. Adult Immunization 2010 MMR Vaccine Segment This material is in the public domain This information is valid as of May 25, 2010

2. Measles-Mumps-RubellaVaccine (MMR) • Contains live attenuated viruses • 1-dose efficacy varies from 80% (mumps) to 95% (measles and rubella) • Duration of immunity probably lifelong • Schedule is 2 doses • All adults born in 1957 or later should have documentation of at least 1 dose (or other evidence of immunity)

3. Adults at High Risk forMeasles • College students • International travelers • Healthcare personnel

4. MMR VaccineContraindications • Severe allergic reaction to vaccine component or following prior dose • Pregnancy • Immunosuppression

5. Measles Vaccine and HIV Infection • MMR recommended for persons with asymptomatic and minimally symptomatic HIV infection • NOT recommended for persons with evidence of severe immuno-suppression • Prevaccination HIV testing of an otherwise healthy person not recommended

6. MMR Vaccination of Women of Childbearing Age • Ask if pregnant or likely to become so in next 4 weeks • Exclude those who say "yes“ • For others • explain theoretical risks • vaccinate

7. MMR VaccinePrecautions • Moderate or severe acute illness • Recent receipt of a blood product • History of thrombocytopenia or thrombycytopenic purpura

8. MMR Adverse Reactions Fever 5%-15% Rash 5% Joint symptoms 25% Thrombocytopenia <1/30,000 doses Parotitis rare Deafness rare Encephalopathy <1/1,000,000 doses

9. National Center for Immunization and Respiratory DiseasesContact Information • Telephone (800) CDC-INFO • Email nipinfo@cdc.gov • Website http://www.cdc.gov/vaccines/ • Broadcast Updates and Resources Web Page http://www.cdc.gov/vaccines/ed/webcasts.htm