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Adult Immunization 2010 Varicella Vaccine Segment

Adult Immunization 2010 Varicella Vaccine Segment. This material is in the public domain This information is valid as of May 25, 2010. Varicella Vaccine. Live virus vaccine Efficacy 70%-90% against any varicella disease 95%-100% against severe disease

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Adult Immunization 2010 Varicella Vaccine Segment

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  1. Adult Immunization 2010 Varicella Vaccine Segment This material is in the public domain This information is valid as of May 25, 2010

  2. Varicella Vaccine • Live virus vaccine • Efficacy • 70%-90% against any varicella disease • 95%-100% against severe disease • Schedule for adults - 2 doses separated by at least 4 weeks

  3. Varicella VaccineContraindications • Severe allergic reaction to vaccine component or following prior dose • Pregnancy • Immunosuppression

  4. Varicella VaccineUse in Immunocompromised Adults • Most immunocompromised persons should not be vaccinated • Vaccine is effective and safe in persons with impaired humoral immunity • passive antibody used to treat the condition may interfere with vaccine • Vaccinate persons with isolated humoral immunodeficiency

  5. Varicella VaccineUse in Persons with HIV Infection • Consider varicella vaccination for HIV-infected adults with CD4+ T-lymphocyte count of 200 mm3 or higher • 2 doses separated by 3 months

  6. Varicella VaccinePrecautions • Moderate or severe acute illness • Recent receipt of a blood product • administer at least 2 weeks prior to receiving blood product • delay for at least 3 months following administration of blood, immune globulin, or other blood products (see table for guidance)

  7. Varicella VaccineAdverse Reactions • Injections site complaints - 20% • Rash - 4% - 6% • may be maculopapular rather than vesicular • average 5 lesions • Temperature 102°F or higher - 10% - 15%

  8. National Center for Immunization and Respiratory DiseasesContact Information • Telephone (800) CDC-INFO • Email nipinfo@cdc.gov • Website http://www.cdc.gov/vaccines/ • Broadcast Updates and Resources Web Page http://www.cdc.gov/vaccines/ed/webcasts.htm

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