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Chapter 7: the Nervous System. Bio 24. Organization of the nervous system. Organization of the nervous system. Our responses to stimuli may be voluntary or involuntary or both
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Organization of the nervous system • Our responses to stimuli may be voluntary or involuntary or both • Example: in response to low blood pressure, you may contract smooth muscles to decrease the diameter of your blood vessels, AND feel thirsty, causing you to take a drink
Central and peripheral nervous systems • Your central nervous system (CNS) consists of your brain & spinal cord • Your peripheral nervous system (PNS) consists of all the nerves that carry information to and from your CNS
Cells of the nervous system • There are two main types of cells in the nervous system: • Neurons: communicate with other cells using electrical and chemical signals • Neuroglia: support and insulate the neurons; FAR more abundant than neurons
Parts of a neuron • Cell body • Dendrites: receive signals from other neurons • Axons: send signals to other cells • Schwann cells (neuroglial cells) wrap around the axons to form myelin
Schwann cells form myelin in the PNS • Schwann cells form myelin by wrapping around PNS neurons • Oligodendrocytes form myelin by wrapping around CNS neurons • “White matter” is nerve tissue wrapped in myelin (axons), “gray matter” is unmyelinated (usually cell bodies)
Multiple sclerosis • Autoimmune disease that attacks myelin in both the CNS & PNS • Multiple functions of the nervous system may be impaired
Many types of sensory receptors • In response to physical stimulation, sensory receptor cells create electrical signals that travel to the central nervous system • Specialized senses (hearing, sight, smell & taste) have special receptor cells to be discussed in chapter 8
Electrical signals generated by neurons are action potentials • Electrical energy is the result of movement of ions • When neurons generate action potentials it involves ions moving across the cell’s plasma membrane • An action potential is an electrical signal that starts in a neuron and travels down the axon
The synapse • When electrical signals reach the end of axons, they trigger the release of chemicals from the axon terminal • The space between the axon terminal and another cell is called the synaptic cleft and the connection between the two is called the synapse
Neurotransmitters are released at the synapse • Neurotransmitters are chemical signals released from a neuron’s axon terminal onto a target cell • The target cell may be a neuron, too, or another cell type • Many recreational and therapeutic drugs work by influencing the action of neurotransmitters
Reflexes • A reflex is an automatic response to a stimulus • Reflexes can control either skeletal muscles (somatic reflexes) or involuntary muscles (autonomic reflexes) • Reflexes are integrated by your spinal cord NOT your brain, hence they are not conscious actions
4 major regions of the brain • Brain stem: controls breathing and blood pressure; many nerves pass through • Cerebellum: controls movement • Diencephalon: integrates sensory information & mediates emotional response • Cerebrum: controls all “higher thought”
Areas of the cerebrum are specialized for different functions
The cerebral cortex receives sensory information and sends motor information
The CNS is vulnerable to damage • Cells of the central nervous system have a very limited ability to regenerate themselves • The cells themselves are soft and easily damaged (your brain has the consistency of tofu) • The blood-brain barrier refers to the fact that capillaries in the brain are less permeable than those in other parts of the body; this helps protect your brain from damage due to chemicals in your bloodstream
Bones and meninges protect the CNS • The meninges consist of the: • dura mater • arachnoid mater • pia mater • layers of connective tissue membrane that protect the brain and spinal cord • Meningitis is inflammation of the meninges caused by viral or bacterial infection; can be serious or fatal!
Cerebrospinal fluid in and around the brain and spinal cord also protects it
Traumatic brain injuries • Most often caused by car accidents • Concussion: a mild traumatic brain injury; may result in temporary loss of consciousness • Intracranial hemorrhage: bleeding in the brain; can damage brain tissue • Cerebral edema: swelling of the brain; sometimes part of the skull is temporarily removed to treat this
Stroke • Stroke is the result of a blood clot that blocks blood flow to part of the brain; if brain tissue is deprived of blood for even a few minutes, it dies • Aphasia, or reduced ability to produce or understand language, is common after stroke affecting the left hemisphere
The spinal cord • Spinal nerves carry information both to and from the CNS • The nerves then split and the sensory information goes in through a structure called the dorsal root; motor information goes out through the ventral root
The spinal cord • Dorsal horns (gray matter) contain interneurons that connect neurons to each other • White matter of the spinal cord is myelinated axons carrying info up and down
The sympathetic and parasympathetic divisions • Sympathetic nervous system is activated under “fight or flight conditions” • Blood flow to muscles increases • Pupils of eyes dilate • Digestion is inhibited • Heart rate increases • Parasympathetic nervous system is activated under “rest and digest” conditions • Table 7.3 in your book lists several specific effects each of these has!