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Leukemia . By:Ashley Druck. Definition. Is cancer that starts in the blood, forming tissues such as the bone marrow and causes large numbers of blood cells to be produced and enter the bloodstream. History. Was first diagnosed in 1845 in Scotland.
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Leukemia By:AshleyDruck
Definition • Is cancer that starts in the blood, forming tissues such as the bone marrow and causes large numbers of blood cells to be produced and enter the bloodstream.
History • Was first diagnosed in 1845 in Scotland. • This disease was named Leukemia because Leukemia means white blood and if you have Leukemia you have a higher count of white blood cells.
White blood cells: Fights infections • Red Blood Cells: Carries oxygen to all parts of the body. • Platelets: Helps your blood clot. • Your body starts to make abnormal white blood cells. They grow faster than normal cells; they don’t stop growing when they should Healthy Bone Marrow Makes: When you have Luekemia
Several Types • Lymphocytic- affects white blood cells called lymphocytes. • Myelogenous-affects white blood cells called myelocytes. • Acute- gets worse very fast, may make you very sick right away. • Chronic- gets worse slowly, may not cause symptoms for years.
Causes • They don’t know the cause • Risk Factors: • Exposed to large amounts of radiation • Exposed to certain chemicals • Had some type of chemotherapy from another cancer. • Have down syndrome or another genetic problem • Smoke
Symptoms; Depends on what type you have. • Getting lots of infections • Feeling tired or weak • Losing weight or not feeling hungry • Fever/Night Sweats • Headaches • Bruising or bleeding easily • Bone, joint pain • Swollen or painful stomach • Swollen lymph nodes
Diagnosed • The doctor will ask you questions • Do a physical exam • Order blood work; look for high levels of white blood cells and low levels of other cells. • Do a bone marrow biopsy- tells the doctor what type of leukemia you have.
Treatment Options • Chemotherapy: power medicines to kill cancer cells. Main treatment • Radiation Treatment: high dose of X-Rays to destroy cancer cells • Clinical trials: Research projects to test new medicines and other treatments. • Stem Cell Transplant: Stem cell can rebuild your supply of normal blood cells. • Biological therapy: use of special medicines to improve your body’s natural defenses against cancer.
Locus/ Linkage • This gene acts as master control during the transition of primitive blood forming cells into white blood cells. • The mutations were found in GATA2 gene.
Age of Onset • 30,000 new cases are discovered every year and 90% of them are found in adults. • Kids can get it to though, they are just more likely to be cured and to live through it. • It is a major cause of death in men ages 15-35. • Kids from ages 2-8 are more likely in getting leukemia but any age kid can develop it.
Affected Groups • Men cover about 56% of new cases each year • Most new occurred cases of cancer in kids under 15 is Leukemia. • Caucasians are more likely to get Leukemia than any other ethnic groups.
Inheritance Leukemia shows up at random times. Sometimes inheritance and other environmental factors play a role, but most times it is just random. There are only a few known cases where the parents pass it down to their kids
Recent Progress • Found when they added the drug Rituxan to the drug fludara it slows the progression of the Leukemia. • Developing new more effective therapies, that is improving survival and a new life quality for patients.
Interesting Case • A family friend of mine had Leukemia but before she had Leukemia she had breast cancer and from that she got Leukemia. Hers was getting so bad they really couldn’t do anything. But they were doing research and a clinical study in Florida that they thought might help keep her alive. She left her four young kids here and went to Florida, but there testing couldn’t help her and she died while in Florida. They also tested her family members to see if anyone could give her a bone marrow transplant but none of her family was a match.
Work Cited • Kidshealth.org • http://ezinearticles.com • http://depts.washington.edu • http://ic.steadyhealth.com/history_of_leukemia.html • Sciencedaily.com