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Chem150 - Survey of Biochemistry

Chem150 - Survey of Biochemistry. Introduction. Introduction. The chemistry we will focus on this semester Organic Chemistry The chemistry of carbon Functional groups Biochemistry The chemistry of living systems. Organic Chemistry. Organic Chemistry.

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Chem150 - Survey of Biochemistry

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  1. Chem150 - Survey of Biochemistry • Introduction

  2. Introduction • The chemistry we will focus on this semester • Organic Chemistry • The chemistry of carbon • Functional groups • Biochemistry • The chemistry of living systems

  3. Organic Chemistry

  4. Organic Chemistry • Hydrocarbons represent the starting point • Contain only carbon and hydrogen • Groups include Alkanes, alkenes and alkynes Butane

  5. Organic Chemistry • Organic molecule are organized into functional groups • Many contain elements other than carbon and hydrogen • Oxygen • Nitrogen • Sulfur • Halogens (F, Cl, Br, & I)

  6. Organic Chemistry

  7. Organic Chemistry • Functional Groups • Hydroxyl groups (alcohols) Hydroxyl Group 1-Butanol

  8. Organic Chemistry • Functional Groups • Amino groups (amines) Amino Group 1-Butylamine

  9. Organic Chemistry • Functional Groups • Carbonyl groups (aldehydes and ketones) Aldehyde Group Butanal

  10. Organic Chemistry • Functional Groups • Carboxyl groups (carboxylic acids) Carboxyl Group Butanoic acid

  11. Organic Chemistry • Functional Groups • Functional group affect the physical and chemical properties of organic molecules. Butane (alkane) Butanol (alcohol) Butylamine (amine) Butanoic acid (carboxylic acid) water Butanal (aldehyde)

  12. Organic Chemistry • Functional Groups • chemical structure affects drug or hormone-receptor interactions

  13. Organic Chemistry • Functional Groups • Is this even possible? Or this? http://www.ftc.gov/opa/2004/04/040429canspam.shtm

  14. THC and “designer” drugs: is there a case against “Spice” or K2?

  15. THC and “designer” drugs D9 tetrahydrocannabinol Anandamide JWH-018 ?

  16. ORGANIC MOLECULE IN THE NEWS: Bisphenol A

  17. Nalgene polycarbonates What chemical questions would you want to have answered to decide ?

  18. PHARMACOPHORE IN THE NEWS: Bisphenol A http://e.hormone.tulane.edu/learning/estrogens.html

  19. Biochemistry • Biological molecules • Amino acids and Proteins • Carbohydrates and Polysaccharides • Nucleotides and Nucleic acids • Lipids (Fats, oils)

  20. Biochemistry • Biological molecules • Aminoacids and Proteins Carboxylic Acid Group Amino Group Alanine

  21. Biochemistry • Biological molecules • Carbohydrates and Polysaccharides Glucose

  22. Biochemistry • Biological molecules • Lipids (Fats, oils) Triglyceride

  23. Biochemistry • Biological Macromolecules • Proteins, Polysaccharides and Nucleic Acids • Metabolism • Taking things apart • Putting things together • Obtaining and using energy • Regulation of processes.

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