1 / 17

Innate + adaptive immunity

Innate + adaptive immunity. Innate immunity only. From Thomas C. G. Bosch (Kiel). Innate Immunity (NK cells, DC, Neutrophils, Monocytes/Macrophages). Effector Functions. « Pathogens ». Initiation of Ag-specific response. Adaptive Immunity (T and B Lymphocytes ). Figure 2-1.

tavita
Download Presentation

Innate + adaptive immunity

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Innate + adaptive immunity Innate immunity only From Thomas C. G. Bosch (Kiel)

  2. Innate Immunity (NK cells, DC, Neutrophils, Monocytes/Macrophages) Effector Functions « Pathogens » Initiation of Ag-specific response Adaptive Immunity (T and B Lymphocytes )

  3. Figure 2-1

  4. Toll-like Receptors (TLR):innate immune sensors Toll and TLRs

  5. Nat Rev Immunol. 2004 Jul;4(7):521-7. The road to Toll. Lemaitre B. Centre de Genetique Moleculaire, Centre National de la Recherche Scientifique, F-91198 Gif-sur-Yvette, France. lemaitre@cgm.cnrs-gif.fr

  6. Toll-like receptors ssRNA IMQ CpG IMQ dsRNA Flagellin LPS Zym, LP PG, LP LP 1 2 3 4 5 6 7 8 9 10

  7. Figure 2-16 part 1 of 2

  8. Figure 2-16 part 2 of 2

  9. Figure 2-17

  10. hKIR TREM Ig-SF NCR m PIR h LIR (ILT) NKRP-1 mLY49 NKG2D C-type Lectins Mannose Rec. (MR, Endo180, DEC205, PLA2R) DC-SIGN receptors Dectin-2 (NCCL) Langerin BDCA-2 (DLEC) TLR Others (LRR, CARD,…) NOD molecules TLR

  11. Figure 2-5

More Related