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Laboratory of SYSTEMS BIOLOGY

Trout. Rat. Laboratory of SYSTEMS BIOLOGY. Comparative experimental and computational studies on cardiac myocytes. Animal Models: Rat, trout, wild type and transgenic mouse. Bioenergetics Influence of intracellular compartmentation and diffusion restrictions on bioenergetics

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Laboratory of SYSTEMS BIOLOGY

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  1. Trout Rat Laboratory of SYSTEMS BIOLOGY Comparative experimental and computational studies on cardiac myocytes Animal Models: Rat, trout, wild type and transgenic mouse Bioenergetics Influence of intracellular compartmentation and diffusion restrictions on bioenergetics Mechano-Energetics Interaction between mechanics and energetics of the heart Electrophysiology Measurements of intracellular ion concentrations Calcium Signaling Examination of the causes of unstable calcium regulation Scientific Computing Open source scientific software tools: Image enhancement, data acquisition and analysis Cardiac Myocytes

  2. Laboratory of SYSTEMS BIOLOGY Cell membrane (green), F-Actin (red) Active Collaborations: Shey-Shing Sheu, University of Rochester, USA Craig A. Lygate, Oxford University, UK Eric A. Sobie, Mount Sinai School of Medicine, USA Funding Agencies: Wellcome Trust (UK) Estonian Ministry of Education and Research Estonian Science Foundation

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