1 / 51

Muscular System

Muscular System. As with the skeltal system most of the muscular system also develops from the mesodermal germ layer Smooth muscle develops from splanchnic mesoderm which surrounds gut /derivatives. • Cardiac muscle develops from splanchnic mesoderm which surrounds the heart tube.

thuy
Download Presentation

Muscular System

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Muscular System • As with the skeltal system most of the • muscular system also develops from the • mesodermal germ layer • Smooth muscle develops from splanchnic • mesoderm which surrounds gut /derivatives. • • Cardiac muscle develops from splanchnic • mesoderm which surrounds the heart tube.

  2. TRUNK MUSCULATURE • Skeletal muscle of the • trunk develops from • paraxial mesoderm • (which forms somites & • somitomeres) • • Somites differentiate

  3. Somites differentiate • into:- • 1. Sclerotome → Axial • skeleton & • 2. Dermomyotome → • a.Dermatome dermis • and subcut tissues & b. • Myotome segmental • muscles (& takes with it • its own segmental nerve).

  4. FATE OF MYOTOME CELLS • Myotome cells split • off, move to their • definitive locations, & • become elongated & • spindle shaped • (called myoblasts) • Many myoblasts fuse • to become • Multinucleated muscle fibres.

  5. Myofibrils appear in • cytoplasm. • By 12/52 cross • striations typical for • skeletal muscle • appear.

  6. Somites: form body wall musculature. It forms a dorsal epimere & a • ventral hypomere. • The epimere forms the vertebral extensors; while the hypomere forms • the muscles of the body wall and limbs. • Note the different innervation viz. dorsal and ventral primary rami

  7. Somitomeres • same process in head and neck region i.e. form myoblasts which will form extra ocular eye muscles, face, larynx, tongue etc

  8. Head Musculature

  9. Limb Musculature • Condensation of mesenchyme near the base of limb buds (7th week) • Mesenchyme is derived from dorsolateral cells of somites • Migrate into limb bud to form the muscles • Connective tissue dictates the pattern of muscle formation • Upper limb buds lie opposite the lower five cervical and upper two thoracic segments

  10. Limb Musculature • Lower limb buds lie opposite lower foua lumbar and upper two sacral segments • There is a 180° medial rotation of the lower limb compared to developing upper limb (angle of flexion differs)

  11. Cardiac Muscle • Develops from splanchnic mesoderm surrounding the endothelial heart tube • Myoblasts adhere to one another by intercalated discs • Myofibrils develop as in skeletal muscle but do not fuse • Few special bundles become visible (Purkinje fibers)

  12. Smooth Muscle

  13. Clinical Correlations

  14. BODY CAVITIES,MESENTERIES &DIAPHRAGM

  15. INTRAEMBRYONIC COELOM

  16. INTRAEMBRYONIC COELOM • Appears as isolated spaces in the lateral mesoderm • In the 4th week, the spaces fuse to form a single horseshoe-shaped (U-shaped) cavity • The coelom divides the lateral mesoderm into: • Somatic (parietal) layer: under ectoderm • Splanchnic (visceral) layer: over endoderm

  17. Somatopleure = somatic mesoderm + overlying ectoderm • Splanchnopleure =splanchnic mesoderm + underlying endoderm

  18. INTRAEMBRYONIC COELOM

  19. DERIVATIVES: It gives rise to three body cavities: • A pericardial cavity: the curve of U • Two pericardioperitoneal canals (future pleural cavities): the proximal parts of the limbs of U • Two peritoneal cavities: the distal parts of the limbs of U • Each cavity has a parietal layer (derived from somatic mesoderm) & a visceral layer (derived from visceral mesoderm) • FUNCTION: It provides space for the organs to develop & move

  20. DEVELOPMENT OF PERITONEAL CAVITY • Major part of intraembryonic coelom • Develop from the distal parts of the limbs of the U-shaped cavity • Originally, it is connected with extraembryonic coelom (midgut herniates to the outside through this connection) • At 10th week, it looses its connection with extraembryonic ceolom (when midgut returns to abdomen)

  21. DEVELOPMENT OF PERITONEAL CAVITY • Originally, there were 2 peritoneal cavities • After lateral folding of embryo, the peritoneum becomes a single cavity HOW?

  22. MESENTERIES • A MESENTERY is a double layer of peritoneum that begins as an extension of the visceral peritoneum covering an organ • The mesentery connects the organ to the body wall and transmits vessels and nerves to it • Transiently, the dorsal & ventral mesenteries divide the peritoneal cavity into right & left halves • The ventral mesentery disappears EXCEPT where stomach develops • (WHY?)

  23. PERICARDIAL CAVITY • Develops from the curve of the U-shaped cavity • During formation of head fold, the heart & pericardial cavity move ventrocaudally & become anterior to the foregut (esophagus) • It is bounded by an outer somatic & an inner visceral layer, forming the serous pericardium

  24. PERICARDIAL CAVITY • Originally, it is connected with the 2 pericardioperitoneal canals • Later on, it become separated from the 2 pericardioperitoneal canals HOW?

  25. PERICARDIAL CAVITY • Originally, the bronchial buds are small relative to the heart • Bronchial buds grow laterally into pericardioperitoneal canals (future pleural cavities) • Pleural cavities expand ventrally around heart & splits mesoderm into: • Outer layer: forms thoracic wall • Inner layer:pleuropericardial membrane

  26. PLEUROPERICARDIAL MEMBRANES • THE PARTS SURROUNDING THE SEROUS PERICARDIUM: form the fibrous pericardium • THE PARTS BEHIND THE HEART: fuse with the ventral mesentery of the esophagus (at 7th week), forming the mediastinum & separating pericardial from pleural cavities • N.B.: The right pleural cavity separates from pericardial cavity earlier than left

  27. PLEURAL CAVITIES • Develop from the 2 pericardiperitoneal canals • Originally, they are connected with pericardial & peritoneal cavities • Later on, they become separated from: • Pericardial cavity • Peritoneal cavity (HOW?)

  28. PLEUROPERITONEAL MEMBRANES • Produced when developing lungs & pleural cavities expand into the body wall • During 6th week, they fuse with dorsal mesentery of esophagus & septum transversum, separating pleural cavities from peritoneal cavity • N.B.: The right pleural cavity separates from peritoneal cavity earlier than left

  29. DEVELOPMENT OF DIAPHRAGM

  30. DEVELOPMENT OF DIAPHRAGM • The diaphragm develops from: • Septum transversum: forms the central tendon • Dorsal mesentery of esophagus: forms the right & left crus • Muscular ingrowth from lateral body wall:posterolateral part (costal part) • Pleuroperitoneal membranes: small portion of diaphragm

  31. SEPTUM TRANSVERSUM • At 3rd week, it is in the form of mass of mesodermal tissue in the cranial part of embryo (opposite the 3rd, 4th & 5th cervical somites) • At 4th week (during formation of head fold), it moves ventrocaudally forming a thick incomplete partition between thoracic & abdominal cavities • At 6th week, it expands & fuse with dorsal mesentery of esophagus & pleuroperitoneal membranes to form the diaphragm

  32. INNERVATION OF DIAPHRAGM • Myoblasts from 3rd, 4th & 5th cervical somites migrate into diaphragm & bring their nerve fibers from them • Nerve fibers derived from ventral rami of 3rd, 4th & 5th cervical nerves fuse to form phrenic nerve that elongate to follow the descent of diaphragm • Both motor & sensory supply of the diaphragm is derived from phrenic nerve • The part of diaphragm derived from lateral body wall receives sensory fibers from lower intercostal nerves

  33. ANOMALIES OF DIAPHRAGM • CONGENITAL DIAPHRAGMATIC HERNIA • EVENTRATION OF DIAPHRAGM • CONGENITAL HIATAL HERNIA

  34. CONGENITAL DIAPHRAGMATIC HERNIA

  35. CONGENITAL DIAPHRAGMATIC HERNIA • A posterolateral defect of diaphragm • Cause: defective formation and/or fusion of pleuroperitoneal membrane with other parts of diaphragm • Effects: • Herniation of abdominal contents into thoracic cavity • Peritoneal & pleural cavities are connected with one another • The defect usually occurs in the left side (WHY?)

  36. EVENTRATION OF DIAPHRAGM

  37. EVENTRATION OF DIAPHRAGM • Cause: failure of muscular tissue from body wall to extend into pleuroperitoneal membrane on one side • Effects: superior displacement of abdominal viscera (surrounded by a part of diaphragm forming a pocket)

  38. CONGENITAL HIATAL HERNIA • Herniation of part of the stomach through a large esophageal hiatus (opening)

  39. Reference • clanatomy.ukzn.ac.za/...Embryology/EMBRYOLOGY_OF_MUSCULAR • HENRY Gray 1821-1865 anatomy of the human body. • http://www.youtube.com/watch?v=8VFAF_piggl

More Related