200 likes | 330 Views
Treatments for Coronary Artery Disease. Medicine PTCA CABG. Medicine. Types of medicines used in coronary artery disease. drugs to prevent clot formation drugs to break down clots already formed cholesterol-lowering drugs blood pressure medications.
E N D
Treatments for Coronary Artery Disease Medicine PTCA CABG
Types of medicines used in coronary artery disease • drugs to prevent clot formation • drugs to break down clots already formed • cholesterol-lowering drugs • blood pressure medications
When do we treat coronary disease with MEDICINE only? • stable coronary artery disease • no high risks for heart attack
What is PTCA? • Percutaneous (through the skin) transluminal (inside the blood vessel) coronary (relating to the heart) angioplasty (blood vessel repair). • balloon angioplasty • When a stent is also used, the procedure is called a Percutaneous Coronary Intervention (PCI). • stenting
Stents • self expandable • balloon expandable • drug eluting
Drug Eluting Stents • Paclitaxel • Sirolimus (Rapamycin) • Heparin • Angiopeptin • Abciximab • Phosphorylcholine • Poly-l-lactic stent • Hybrid revascularization
Restenosis • after angioplasty, the vessel begins to heal, the artery contracts, and the lumen narrows • restenosis is more likely to occur after POBA (balloon angioplasty) than after stenting
When do we treat coronary disease with PTCA (Angioplasty or Stent)? • stable coronary artery disease with risks • previous heart attack • failed medication • 1 or 2 coronary arteries involved
If stents are more effective than balloon angioplasty, why not always use a stent? • Stents are difficult to deliver across tight bends in blood vessels (particularly if they have a lot of calcium deposits in the wall) and are not usable in very small blood vessels. There are other types of technical considerations that also come into play. Today, it is estimated that stents are employed in nearly 50-75% of cases.
CABG Coronary Artery Bypass Graft
vessels used for CABG • internal mammary artery • radial artery • great saphenous vein
IMA= internal mammary artery RA = radial artery SVG = great saphenous vein
CABG procedure types • heart lung machine • off-pump bypass graft • stabilizer
When do we treat coronary disease with CABG? • multiple coronary arteries involved • left main coronary artery affected • patient requires valve surgery also • Diabetes Mellitus • poor left ventricular function • recurrent restenosis after PCI
VIDEO • http://www.youtube.com/watch?v=jlNjyJgi5WA