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Making Progress Professor Martin Gibson, Director GM CLRN

Making Progress Professor Martin Gibson, Director GM CLRN . Local Health and Wellness Challenges . Building Links and Success. Improve and Innovate. Can data make us well?. Need new tools to make sense of the quantity and quality of information available

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Making Progress Professor Martin Gibson, Director GM CLRN

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  1. Making Progress Professor Martin Gibson, Director GM CLRN

  2. Local Health and Wellness Challenges

  3. Building Links and Success

  4. Improve and Innovate Can data make us well? • Need new tools to make sense of the quantity and quality of information available • Unlocking important information from messy data • Joining care across traditional boundaries, including academia, social care and health

  5. Real-world Evidence Engine? DROUGHT of EXPERTISE BLIZZARD ofMODELS/METHODSand LITERATURE Diabetes TSUNAMI of DATA Research Cancer Silo k… Commissioning Governance PROLIFERATION of PIPELINES

  6. Looking Behind the Codes UK Diabetes Prevalence from Different Databases Consider the GP annotation on a diabetes code “DM r/o” From E. Kontopantelis & T. Doran

  7. Raw NHS Data: Too Messy? First glitazoneRx Mean log(ALT) before Mean log(ALT) after Fitted trends do not join evidence of glitazone effect on ALT Trends in liver function among patients with type 2 diabetes:messy real-world data; effect consistent with best evidence. Improved liver function (pooled) = 0.15 (se=0.009), p<1x10-59 Similar effect alone or with other drugs {G = 0.12; G+M = 0.16; G+S = 0.16; G+S+M = 0.15G = glitazone, M = metformin, S = sulponylurea} From M. Sperrin

  8. Improve and Innovate Improving access to research • Implementation of research knowledge • Fifteen years from recommendations to complete uptake • Access to better treatments • More informed choice, enabling consent

  9. Safety and Quality Benefits for everyone Supporting patients - helping them know what they can do next and to contribute to their own care Supporting clinicians – providing the information required to make safer, better decisions linked with other healthcare colleagues Supporting commissioners - Providing the evidence base for improvement and measurement of performance over time Supporting research – supporting and evaluating new treatments and understanding the wider public health picture

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