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yaz……… What is it? Indications? How to use it? Side effects? Drug interactions?

yaz……… What is it? Indications? How to use it? Side effects? Drug interactions?. Yaz is acombination of *drospirenone *ethyl estradiol It was approved by FDA 2006. The main indication is as oral cotraceptive pills But..it can also be used for the Rx of acne. It treats acne in women

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yaz……… What is it? Indications? How to use it? Side effects? Drug interactions?

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  1. yaz……… What is it? Indications? How to use it? Side effects? Drug interactions?

  2. Yaz is acombination of • *drospirenone • *ethyl estradiol • It was approved by FDA 2006

  3. The main indication is as oral cotraceptive pills • But..it can also be used for the Rx of acne

  4. It treats acne in women At least 14 years old who doesn’t mind to control pregnancy

  5. M.O.A: • Acne is a skin condition results by an androgenic stimulation of sebum production • Yaz…increases binding globulen{SGBG} and decrease free Testosterone

  6. How can you use it……? 28 –day dosing 1 active tab daily for 24 days Followed by 1 inert tab for 4 days After 28 days Start anew course……..

  7. What about food interaction……? *rate of absorbtion is decreased under fed{high fat meal} *grapefruit increases its bioavalability *yaz has aminor interaction with alcohol

  8. What about drug interactions? Met formin :efficacy of oral hypoglycemic agents and insulen is diminished by yaz Nexium has no drug interactionwith yaz

  9. Yaz side effects : • Major: breast tenderness • Bleeding or spotting b/w menstrual periods • Minor: nausea ,stomach cramps, vomiting

  10. Contraindications………… 1.Pregnant or nursing women 2.History of clot or strock 3.Kidney or liver dz 4.BP 5.Allergy

  11. Thanx for attention Diana alam arandy………

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