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24. All these drugs are available on the market and are administered as sublingual tablets for the prevention of cardiovasc problems or for sevrage de drogues (buprenorphine)All these drugs are available on the market and are administered as sublingual tablets for the prevention of cardiovasc problems or for sevrage de drogues (buprenorphine)
25. Buccal adm of hydrophilic drugs remains experimental as these drugs are not well absorbed from the buccal mucosa unless using absorption enhancers which are often toxic for the cell membranesBuccal adm of hydrophilic drugs remains experimental as these drugs are not well absorbed from the buccal mucosa unless using absorption enhancers which are often toxic for the cell membranes
26. Steady state concentrations in plasma between 1 and 4 hours.Steady state concentrations in plasma between 1 and 4 hours.
27. Buccal absorption appears as a 2 two steps process: 1) drug transfer from the DDS to the buccal epithelium where the drug accumulate 2) drug uptake from some epithelial depot into the bloodstream.Buccal absorption appears as a 2 two steps process: 1) drug transfer from the DDS to the buccal epithelium where the drug accumulate 2) drug uptake from some epithelial depot into the bloodstream.
28. Buccal absorption appears as a 2 two steps process: 1) drug transfer from the DDS to the buccal epithelium where the drug accumulate 2) drug uptake from some epithelial depot into the bloodstream.Buccal absorption appears as a 2 two steps process: 1) drug transfer from the DDS to the buccal epithelium where the drug accumulate 2) drug uptake from some epithelial depot into the bloodstream.
29. Buccal absorption appears as a 2 two steps process: 1) drug transfer from the DDS to the buccal epithelium where the drug accumulate 2) drug uptake from some epithelial depot into the bloodstream.Buccal absorption appears as a 2 two steps process: 1) drug transfer from the DDS to the buccal epithelium where the drug accumulate 2) drug uptake from some epithelial depot into the bloodstream.
30. Buccal absorption appears as a 2 two steps process: 1) drug transfer from the DDS to the buccal epithelium where the drug accumulate 2) drug uptake from some epithelial depot into the bloodstream.Buccal absorption appears as a 2 two steps process: 1) drug transfer from the DDS to the buccal epithelium where the drug accumulate 2) drug uptake from some epithelial depot into the bloodstream.
31. Buccal absorption appears as a 2 two steps process: 1) drug transfer from the DDS to the buccal epithelium where the drug accumulate 2) drug uptake from some epithelial depot into the bloodstream.Buccal absorption appears as a 2 two steps process: 1) drug transfer from the DDS to the buccal epithelium where the drug accumulate 2) drug uptake from some epithelial depot into the bloodstream.
32. Buccal absorption appears as a 2 two steps process: 1) drug transfer from the DDS to the buccal epithelium where the drug accumulate 2) drug uptake from some epithelial depot into the bloodstream.Buccal absorption appears as a 2 two steps process: 1) drug transfer from the DDS to the buccal epithelium where the drug accumulate 2) drug uptake from some epithelial depot into the bloodstream.
33. Buccal absorption appears as a 2 two steps process: 1) drug transfer from the DDS to the buccal epithelium where the drug accumulate 2) drug uptake from some epithelial depot into the bloodstream.Buccal absorption appears as a 2 two steps process: 1) drug transfer from the DDS to the buccal epithelium where the drug accumulate 2) drug uptake from some epithelial depot into the bloodstream.
34. Buccal absorption appears as a 2 two steps process: 1) drug transfer from the DDS to the buccal epithelium where the drug accumulate 2) drug uptake from some epithelial depot into the bloodstream.Buccal absorption appears as a 2 two steps process: 1) drug transfer from the DDS to the buccal epithelium where the drug accumulate 2) drug uptake from some epithelial depot into the bloodstream.
35. Buccal absorption appears as a 2 two steps process: 1) drug transfer from the DDS to the buccal epithelium where the drug accumulate 2) drug uptake from some epithelial depot into the bloodstream.Buccal absorption appears as a 2 two steps process: 1) drug transfer from the DDS to the buccal epithelium where the drug accumulate 2) drug uptake from some epithelial depot into the bloodstream.
36. Buccal absorption appears as a 2 two steps process: 1) drug transfer from the DDS to the buccal epithelium where the drug accumulate 2) drug uptake from some epithelial depot into the bloodstream.Buccal absorption appears as a 2 two steps process: 1) drug transfer from the DDS to the buccal epithelium where the drug accumulate 2) drug uptake from some epithelial depot into the bloodstream.