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Hematopathology, Case 5

Explore the detailed histologic findings of a lymph node with reactive features, including germinal centers of secondary follicles and capsule composition. The preserved architecture hints at a benign process.

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Hematopathology, Case 5

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  1. Hematopathology, Case 5 • Lymph node with reactive features

  2. Describe the histologic findings

  3. Germinal centers of secondary follicles capsule • At low magnification, the lymph node is surrounded by a thin capsule of pink • connective tissue and fibroblasts. • Outside of the node are adipose tissue and blood vessels. • Beneath the capsule are several target-like secondary follicles (secondary • because germinal centers are present). • Overall, we say this lymph node has “preserved architecture,” • a feature favoring a benign process.

  4. Describe the histologic findings seen on higher power

  5. Follicle G= Germinal Center G Germinal centers show normal spacing in between in each other

  6. Describe the histologic findings on high power

  7. Germinal center showd normal mixed elements of lymphoid cells and histiocytes. Germinal center is surrounded by normal mantle cells

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