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Hematopathology, Case 5. Lymph node with reactive features. Describe the histologic findings. Germinal centers of secondary follicles. capsule. At low magnification, the lymph node is surrounded by a thin capsule of pink connective tissue and fibroblasts.
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Hematopathology, Case 5 • Lymph node with reactive features
Germinal centers of secondary follicles capsule • At low magnification, the lymph node is surrounded by a thin capsule of pink • connective tissue and fibroblasts. • Outside of the node are adipose tissue and blood vessels. • Beneath the capsule are several target-like secondary follicles (secondary • because germinal centers are present). • Overall, we say this lymph node has “preserved architecture,” • a feature favoring a benign process.
Follicle G= Germinal Center G Germinal centers show normal spacing in between in each other
Germinal center showd normal mixed elements of lymphoid cells and histiocytes. Germinal center is surrounded by normal mantle cells