The Macromolecules of Cells: Carbohydrates Lipids Proteins Nucleic Acid

1. The Macromolecules of Cells:CarbohydratesLipidsProteinsNucleic Acid

2. Organic Molecules * Organic molecules are found in living things (vs. Nonorganic) * Referred to as “macromolecules” -- Carbohydrates -- Lipids -- Proteins -- Nucleic Acids

3. Organic molecules are made of carbon and can form a huge variety of carbon backbone chains.

4. Macromolecules (polymers) are formed from smaller building blocks called monomers. PolymerMonomer carbohydrates monosaccharides proteins amino acids nucleic acids nucleotides Lipids “none”

5. Carbohydrates Carbohydrates (sugars) serve as 1) quick energy and short-term energy storage 2) they play a structural role in plants, bacteria, and insects 3) many end in the suffix “ose”

6. Monosaccharides • Monosaccharides are sugars that are made up of only one sugar. • There are only 3 monosaccharides Glucose Fructose Galactose

7. Monosaccharide -- one sugar carbohydrate Glucose

8. Disaccharides • Disaccharides are made out of two simple sugars (monosaccharides) Sucrose (table sugar) -- glucose + fructose Maltose (malt sugar) -- glucose + glucose Lactose (milk sugar) -- galactose + glucose

9. A disaccharide is made from linking two monosaccharides together.

10. Reactions • The making or breaking of disaccharides uses a molecule of water • Condensation: reaction makes a disaccharide from two monosaccharides and removes a water molecule in the process. • Hydrolysis: reaction breaks down a disaccharide by adding a water molecule to satisfy the exposed bonding sites on the two new monosaccharides.

11. Condensation Reaction • Water is removed to allow the two sugars to bond together.

12. Hydrolysis Reaction • Water is added so O- and OH+ can be added to exposed bonding sites. • Satisfies bonds

13. Polysaccharides Larger sugars are made from linking many glucose moleculesStarchGlycogenCelluloseChitin

14. Examples of Polysaccharides: starch -- (helical structure) energy storage in plants glycogen cellulose -- (unbranched) found in plants for structure. It is not available as an energy source because of structure. Chitin – found in the exoskeleton of insects and crustaceans (highly branched) quick energy for animals

15. Starch • Starch is a storage molecule for plants. It is stored in structures called plastids. • Starch is high in energy and is stored energy for the plant.

16. Glycogen • Glycogen is a molecule that is used by animals for temporary storage of energy. If not utilized, energy will be stored as fat.

17. Chitin • Chitin is a polysaccharide found in exoskeletons of crustaceans and insects.

18. Cellulose • Polysaccharide found in the cell walls of plants. Strong molecule used for structure and support of the plant cell.

19. Lipids *Lipids serve as long-term energy stores in cells, form membranes, and serve as hormones and insulation. Lipids do not dissolve in water!!! Main reason why lipids are classified together; all other molecules are soluble in water

20. Structure of Triglycerides Formed from a glycerol molecule and three fatty acid molecules.

21. Fatty acids are long chains of carbons with many hydrogens attached. Full of energy since all bonds are potential energy for an organism. Fatty acids may be saturated fatty acids or unsaturated fatty acids. Fatty Acid Chains

22. Saturated Fats have no double bonds Found in tropical oils and animal fats All carbons are “saturated” with hydrogens. Straight chains Solid at room temp. Unsaturated Fats have varying numbers of double bonds Common in plants All carbons are not fully bonded with hydrogens Chains are bent at double bonds Liquid at room temp. Saturated vs. Unsaturated“bad for you” “good for you”

23. Some lipids are phospholipids that form cell membranes. These only have two fatty acids chains. Glycerol head is hydrophilic -- loves water Fatty Acid tails are hydrophobic -- hate water

24. Other lipids are steroids -- no fatty acid chains. Examples: Steroids -- Cholesterol (thickens arteries and is important in cell membrane) Hormones (estrogen and testosterone) Waxes

25. Proteins Proteins: 1. Serve as structural proteins (cartilage, fingernails, hair, etc.) 2. Act as enzymes to speed reactions 3. Serve as transport carriers 4. Act as antibodies 5. Allow materials to cross membranes

26. Proteins are polymers of amino acids.

27. Water is removed when joining two amino acids.

28. Proteins have levels of organization.

29. Protein Organization • Primary Structure (1°) -- linear chain of amino acids. Number and sequence of amino acids varies. • Secondary Structure(2°) -- shortening of amino acid chain by coiling or pleating • Tertiary Structure (3°) -- further folding of chain to create a more compact structure • Quaternary Structure (4°) -- only some proteins have this structure which is two or more chains bonded together.

30. Nucleic Acids Nucleotides are monomers of nucleic acids. Examples include Deoxyribonucleic Acid (DNA) and Ribonucleic Acid (RNA).

32. DNA is double-stranded, with complementary base pairing.