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Current first-line treatment is failing. Tanzania D28 failure SP 70%, AQ 70% (Mutabingwa et al Lancet 2005)Ghana D14 failure CQ 64% (Ansah et al unpublished)Kenya D28 failure SP 46% (Obonyo et al, Trans RSTMH 2003)The Gambia D28 failure CQ 65% (Muller et al TMIH 1996)Malawi D28 failure SP 40%
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1. Deploying artemisinin combination therapy: achievable, but not easy All Party Malaria Group May 2006 Christopher Whitty