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Artificial Skin

Artificial Skin. By: Raymond Litteaur. History of Burns. Before artificial skin was developed, burns covering 50% of the body were considered to be fatal. In 2000, artificial skin cut death rates in people with over 70% burns from 100% to 40%.

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Artificial Skin

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  1. Artificial Skin By: Raymond Litteaur

  2. History of Burns • Before artificial skin was developed, burns covering 50% of the body were considered to be fatal. • In 2000, artificial skin cut death rates in people with over 70% burns from 100% to 40%. • Skin is the body’s largest organs and protects us from physical damage, disease, and controls our body’s temperature.

  3. How Artificial Skin is Made • Skin is usually donated by other donors. • Fibroblasts are removed from the donated skin and are frozen until they are needed. • The fibroblasts are placed on a polymeric mesh scaffolding, gather oxygen, and grow new cells. • The cells are then transferred to a culture system.

  4. Artificial Skin cont. • After 4 weeks the polymer mesh dissolves and leaves behind a new layer of dermal skin. • When the growth cycle is completed, they add more nutrients. • Keratinocytes are added to the collagen and are exposed to air to form epidermal layers. • The skin is now completed and is stored in sterile contains until ready to use.

  5. How Artificial Skin is Used • Artificial skin is already being used for burn victims and soon will be available for other skin disorders. • The skin is not used for a permanent replacement, but to temporary cover the skin until your skin can grow back naturally.

  6. The Future • Because skin is an organ, there are many similarities between skin and other organs. • There is hope to regenerate joints, ears, noses, livers, kidneys, and hearts.

  7. References • GAO Report. 31 May 2005. GAO-05-759T. “Advanced Technology Program: Inherent Factors in Selection Process Are Likely to Limit Identification of Similar Research”<http://www.gao.gov/htext/d05759t.html> • McNulty, Mary F. “Artificial Skin”. <http://www.gale-edit.com/products/volumes/skin.htm> • Smith, Carol. 23 Feb. 2001. “Artificial skin offers genuine hope” <http://seattlepi.nwsource.com/local/burn231.shtml> • T.J. Samson Community Hospital. 1 Jan 2005. “Artificial Skin” <http://tjsamson.client.web-health.com/web-health/topics/GeneralHealth/generalhealthsub/generalhealth/skin&hair&nails/AGING&COSMETIC/skin_artificial.html> • Pictures: • http://www.devicelink.com/mddi/archive/98/05/018.html • http://www.biomed.metu.edu.tr/courses/term_papers/artificial%20skin_cinar.htm

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