From Biofuels and Beyond Inspired Science to Deliver Sustainable Solutions for a Growing World

1. From Biofuels and BeyondInspired Science to Deliver Sustainable Solutions for a Growing World Joel Velasco April 2014

2. Cautionary Note re: Forward Looking Statements This presentation and oral statements accompanying this presentation contain forward-looking statements, and any statements other than statements of historical facts could be deemed to be forward-looking statements. These forward-looking statements include, among other things, sizes of markets that may be addressed by Amyris’s current and potential products, Amyris’s expected product pipeline, sales volumes and average selling prices, production volumes and costs and associated product launch timing expectations, operation of production facilities, commercial relationships, and financial results, that involve risks and uncertainties. These statements and other forward-looking statements that may be provided in the presentation and/or oral statements accompanying it are based on management’s estimates and current expectations and actual results and future events may differ materially due to changes in Amyris’s business and various risks and uncertainties, including those associated with any delays or failures in development, production and commercialization of products, liquidity and ability to fund capital expenditures, Amyris’s reliance on third parties to achieve its goals, and other risks detailed in the “Risk Factors” section of Amyris’s quarterly report on Form 10-K filed on April 2, 2014. Amyris disclaims any obligation to update information contained in these forward-looking statements whether as a result of new information, future events, or otherwise.

3. The Renewable Fuel Standard (RFS2)

4. RFS2 as Imagined LOWER GHG Source: EISA of 2008, U.S. Environmental Protection Agency (RFS-2) Final Rule.

5. RFS2 as Expected Assuming current EPA approach, RFS mandated volumes only increase to the extend total gasoline consumption increases… Blend Wall (10% Gasoline Demand) Source: EISA of 2008, U.S. Environmental Protection Agency (RFS-2) Final Rule.

6. US motor gasoline and diesel consumption (million barrels per day) EIA’s Gasoline and Diesel Consumption Outlook AEO2007 AEO2010 Gasoline AEO2013 AEO2007 AEO2010 AEO2013 Diesel Source: EIA, Annual Energy Outlook 2007, Annual Energy Outlook 2010, Annual Energy Outlook 2013

7. From Biofuels and Beyond

8. Amyris: The Industrial Synthetic Biology Company AMYRIS HQ IN CALIFORNIA • Best-in-Class Tech • Scaled Manufacturing • No Compromise® Products • Founded in 2003 by post-doctoral fellows from the University of California, Berkeley. • Headquartered in the San Francisco Bay Area and with operations in Brazil. • 390 full-time employees, of which one-third are PhDs. • Backed by leading investors and strong partnerships with global brands. AMYRIS PLANT IN BRAZIL

9. Living Factories Delivering Better Products FARNESENE (C15) F&F Molecules Isoprene (C5) Amyris engineers living factories and produces renewable products

10. From Curing Malaria to Better Fuels and ChemicalsDelivering sustainable growth for the worlds leading brands LEADING INVESTORS BIOLDING investment

11. Significant Addressable MarketsDiverse Production Portfolio Today with Improving Profitability

12. Customers Amyris Business Model: Partner-funded product collaboration pipeline, long-term annuity from sales, and industry leading gross margin Strategic & Capability Building Partners RENEWABLE PRODUCTS COLLABORATIONS Over 15 new molecules under contract with 1to 3 new product launch per year PRODUCTION & SALES Expect to double year-on year during the next few years COLLABORATION INFLOWS Expect to continue at $60M to $70M annually DRIVER OF Revenue Growth Earnings through Long-Term Supply Operations OpEx and CapEx PROVIDES CASH FOR R&D OpEx and CapEx Investments in high-value Farnesene Industry leading cash gross margin

13. Amyris Synthetic Biology Technology PlatformThe Science of Genentech with the Engineering of Intel • Developed high-throughput strain engineering system to code and screen over 100,000 yeast strains per month at 95% lower cost. • Generated over 600,000 unique farnesene strains in last year, surpassing 3 million strains. • Tested over 5,000 unique strains in actual fermentation to date and now predict 200,000 liter fermentation performance from 2 liter scale tests. • Reduced time to target isoprenoid molecule from years to months, with thousands of molecules to be accessed. Build: Robotics & Automation Design based on Learnings Test: 100,000 strains/month

14. The Leading Innovator in Industrial Biotech

15. Summary INTEGRATED RENEWABLE PRODUCTS COMPANY

16. For Further Reading Visit our website at investors.amyris.com

19. 2004 Amyris, a “virtual company” licenses back Synthetic Biology patent portfolio. 2005 Amyris opens with a $15M of a five-year grant from the Bill and Melinda Gates Foundation to develop anti-malarialswith Synthetic Biology platform. 2006Amyris takes venture capital to apply SynBio platform to hydrocarbon fuels & chemicals. 2007John Melo, former president of BP’s US Fuels division 2007Amyris team makes “first drops” of renewable diesel in the lab 2008 key technical milestones in anti-malarial drug production partners with Sanofi-Aventis to scale-up & commercialize anti-malarial drug 2008 Amyris opens Pilot Plant for fuel in Emeryville; “first gallons” of diesel 2009 Successful Artemisinin technology transfer to Sanofi-Aventis 2009Amyris produces “first barrels” of diesel 2010 Partnership with Total 2010 IPO (AMRS) 2011 Begin sales of Diesel and Squalane 2012 Amyris produces 2 Million liters of Diesel and Squalane 2013 Launch Artemisinin 70-120 million malaria cures (Sanofi) A Brief History of Amyris