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Eevropis respiraciuli sazogadoebis XX yovelwliuri kongresi

Eevropis respiraciuli sazogadoebis XX yovelwliuri kongresi. The International Twin Study 2009, ( Hungary, Italy, and the United States). 179 monozigoturi da 85 dizigoturi wyvili iqna gamokvleuli F

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Eevropis respiraciuli sazogadoebis XX yovelwliuri kongresi

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  1. Eevropisrespiraciulisazogadoebis XX yovelwliurikongresi

  2. The International Twin Study 2009, (Hungary, Italy, and the United States) • 179 monozigoturida 85 dizigoturiwyviliiqnagamokvleuli F • filtvebisdisfunqciasadasisxlZarRvebiselastiurobisdaqveiTebasSorisinaxamWidrogenetikuriurTierTkavSiri • aTerosklerozsadasasunTqigzebisdaavadebebsaqvTgenetikurikorelacia.

  3. TST-is, Quantiferon-TB GOLD-isa T-SPOT-TB-is SedarebiTidaxasiaTeba • TST-is aqvsaxaltestebzemeti an tolisensitiuroba • T-SPOT-is gamoyenebisasmetipozitiuriSedegiiqnamiRebuli, vidreQuantiferon-TB GOLD-s dros • specifiurobaoriveaxalitestisagacilebiTmaRalia, vidre TST-is • specifiurobaQuantiferon-TB GOLD-isa T-SPOT-TB-is BCG-vaqcinirebulpirebSierTnairia • Sualeduri(ganusazRvreli) SedegebierTnairia • CD4+-isdonemarmoaxdinaraimegavlenatestebisSedegze (461,29±307,49)(I. Latorre, X. Martinez-Lacasa, R. Font, A. Lacoma, J. Puig, C. Tural, E. Cuchi, J. Lite, C. Prat, M. Perez, V. Ausina, J. Dominguez (Terrassa, Badalona, Spain) • CD4+ and CD8+T-ujredebisadmiPPD-specifiurobamcirdebadabaliincidentobisqveynebSi, SedarebiTmaRaliincidentobisqveynebisa (20% vs 64,1%)(C. Giehl (Saarbrucken, Germany))

  4. ERS/ATS-is rekomendacia • upiratesobamieniWosmantus tests (TST)maRaliincidentobisqveynebSi • IFG-assayaqtiuradgamoiyenoslatenturi DA tuberkulozisdiagnostirebisTvisdabaliincidentobisqveynebSi

  5. IP-10 • gama-interferonisproducirebuliproteini (Interferon gamma-induced protein 10 kDa (IP-10). miekuTvnebaCXC jgufiscitokinebs • sekretirdebaIFN-γsapasuxodmonocitebis, endoTeliaruliujredebisadafibroblastebismier • misi done momatebuliavirusuli “C” hepatitis dros • IP-10-is donis 150 pg/mL-zenaklebobaaiv-inficirebulpirebSiarT-TerapiisdawyebamdeiTvlebakeTilsaimedoniSnad • KkvlevebmaaCvenes, romIP-10aseve avlensspecifiurpasuxstuberkulozurimikobaqteriismimarT A • aiv-inficirebulpirebSiIP-10 iyomarkeriM. tuberculosis–is sapasuxod, damoukidebladCD4+Tujredebisdonisa(D. Goletti, A. Raja, B. SyedAhamedKabeer, C. Rodrigues, A. Sodha, O. Butera, S. Carrara, G. Vernet, C. Longuet, S. Tangara, M. Leportier, E. Girardi, P. Lagrange (Roma, Italy; Chennai, Mumbai, India; Lyon, Marcy L'Etoile, Paris, France)

  6. - inovaciurikanSidadiagnostikuritesti- dafuZnebulia or rekombinantulcilaze: ESAT6/CFP10, romelnicarmoipovebian - BCG vaqcinaSi- keTdebadaikiTxebazustadimteqnologiiT, rogorcmantustesti • dafuZnebuliaESAT6/CFP10),

  7. ESAT6/CFP10miRebuliaEscherichia coli-is genetikuradmodificirebulikulturidan.amflifikaciaSemdgomSimoxda M. tuberculosis -is dnm-ze

  8. Diaskintest • SeqmniliaseCenovis sax. moskovissamedicinoakademiismolekulurimedicinissamecniero-kvleviTinstitutSi • gavliliaqvsaprobaciamoskovis, sanqt-peterburgis, samarisdariazanis tub. dawesebulebebSi

  9. Diaskintest • axasiaTebsusafrTxoebismaRaliprofili • maRalispecifiuroba 90-100% (p<0,05) • maRalimgrZnobeloba 98-100% (p<0,05) • hiperergiulireaqcia (vezikulut-nekrotuli forma, limfangiti, limfangoiti) - 2-14% (p<0,05) • mniSvnelovaniimunosupresiisdrostestiSeiZlebaiyosuaryofiTi • saSualebasiZlevavimsjeloTprocesisaqtivobazedaSevafasoTantituberkulozuriTerepiisefeqturoba (gankurnebulebSitestiuaryofiTia)

  10. IFG-assay-Tan SedarebiTDiaskintest: • gacilebiTiafia • arsaWiroebsmaRalteqnologiebs (ELISA, T-SPOT) • arsaWiroebsmaRalkvalificiurlaboratoriul personals

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