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Background. Inconsistent results of AF ablation? Due to Heterogeneity amongst AF populationRole of Trigger removal vs Substrate modification. Hypotheses. Substrate modification can be achieved with linear lesionsIncremental lesion set depending upon disease stageIndividualised approach may standardise single procedure success rates across AF population? Safety and feasibility of this approach.
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1. AF ablation:A single operator’s experience over 3 years (2007 – 2009) Barker D, Patwala A, Damm E,
Hall M, Snowdon R, Gupta D
Liverpool Heart and Chest Hospital, UK
3. Hypotheses
Substrate modification can be achieved with linear lesions
Incremental lesion set depending upon disease stage
Individualised approach may standardise single procedure success rates across AF population
? Safety and feasibility of this approach
4. Methods: Definition of AF groups 131 consecutive patients coming for AF ablation (DG)
Sustained PAF: Patients with PAF, with = 2 of
Any individual AF episodes > 24 hours
History of AF > 5 years
LA size on Echo > 4.5 cm
Age > 65 years
Documented flutter
True PAF
Persistent AF (> 7 days/ Needed Cardioversion)
Longstanding Persistent AF (>12 months)
6. Methods: Prescribed lesion set
True PAF: PVAI
Sustained PAF: + LA roof line
+ RA flutter line
Persistent AF: + LA floor line
LS Persistent AF: + Epicardial CS ablation
+ LA septal ablation
+ CFEs at LAA os
11. Follow-up strategy AAD therapy continued for 2/3 months
Clinic and ECG review at least every 3 months
HRN Contact Line for inter-current support
Ambulatory monitoring to assess symptoms
Early post-op arrhythmias
DC CV if sustained and poorly tolerated
Redo ablation deferred for at least 5-6 months
14. Results: Ablation procedure
15. Mean Follow up duration
17. Symptomatic cure – patient satisfaction
18. 12 month follow up results
19. Freedom from documented AF/ AT
20. Follow up
21. Conclusions
Individualised ablation strategy based on incremental linear lesion placement feasible on practical grounds
Not associated with greater risk of procedural complications
Anatomical (3D mapping based) approach to linear lesion creation associated with acceptably low risk of MAT
This strategy may result in some uniformity of results across the spectrum of AF patients