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Quiz – Page 38

Quiz – Page 38. 1. Give 3 examples of a structural protein. c ollagen, elastin, tubulin, keratin,a ctin. 2. What class of protein in ferretin ?. storage. 3. What does kinesin do? . i t interacts with microtubules to move organelles. 4. What protein carries iron?. transferrin.

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Quiz – Page 38

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  1. Quiz – Page 38 1. Give 3 examples of a structural protein. collagen, elastin, tubulin, keratin,actin 2. What class of protein in ferretin? storage 3. What does kinesin do? it interacts with microtubules to move organelles 4. What protein carries iron? transferrin 5. What class of protein is rhodopsin. receptor

  2. Proteins Homework due today!

  3. Lesson 6 – Nucleic Acids

  4. Nucleic Acids On your desks draw out the structure of a nucleic acid as you remember it.

  5. Nucleotide Structure All nucleotides are made up of a pentose sugar, a phosphate group and a variable nitrogenous base.

  6. Purines and Pyrimidines There are 2 types of nitrogenous bases – purines (double ring structures) and pyrimidines (single ring structures).

  7. Uracil Uracil has one ring so it is a…. pyrimidine In fact it is structurally VERY similar to Thymine.

  8. Nucleotide Structure Up Close

  9. The Phosphodiester Bond The nucleotide monomers are joined by a dehyration synthesis reaction. Phosphodiester bond A bond forms between the phosphate group (C5) of one nucleotide and the hydroxyl group (C3) on the sugar of another.

  10. Base Pairing On your desks write how the bases pair up. Indicate which are purines and which are pyrimidines. Purines always pair with pyrimidines. They are held together by hydrogen bonds. 3 bonds between C andG and 2 bonds between T and A (or U and A).

  11. The Double Helix The 2 strands of the double helix are in an anti-parallel arrangement.

  12. 3’ and 5’ 3’ is read “three prime” and refers to the third carbon on the sugar. Five prime refers to the 5th.

  13. Antiparallel Arrangement showing 3’ and 5’

  14. Double Helix (again) Features of the DNA double helix: One complete turn has a length of 3.4 nm. The diameter of the molecule is 2.0 nm. There is a major groove and a minor groove. The helix is described as right handed.

  15. RNA vs DNA List ways that DNA and RNA differ.

  16. Polymerase Enzymes DNA polymerase is an enzyme that catalyses the formation of the phosphodiester bond between bases. The formation of new strands of DNA occurs from 5’ to 3’ only. This presents a problem during DNA replication as one strand (called the leading strand) can be replicated as the molecule unzips but the other strand (the 3’ to 5’ side, called the lagging strand) needs to be replicated in sections then joined together later by an enzyme called DNA ligase.

  17. Your Task- Nucleic Acids Past Paper Questions You will need to access these in the department. Please DO NOT TAKE past papers home – we have limited numbers. 2004 MC Q8 2005 MC Q 11 2006 MC Q 4 2007 MC Q 7,9 2008 MC Q 6 2009 MC Q 3,4 2. Complete Scholar activities on nucleic acids. 3. Read and make notes on pages 39-42. Make sure your glossary is up to date. DUE Monday (December 3rd)

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