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Organic Compounds. Carbohydrates. Include sugars, glycogen, starches and cellulose Made from Carbon, Hydrogen and Oxygen Usually 1:2:1 ratio (CH 2 O) Divided into groups based on their size. Monosaccharides. AKA simple sugars Building block of carbohydrates
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Carbohydrates • Include sugars, glycogen, starches and cellulose • Made from Carbon, Hydrogen and Oxygen • Usually 1:2:1 ratio (CH2O) • Divided into groups based on their size
Monosaccharides • AKA simple sugars • Building block of carbohydrates • Source of chemical energy for generating ATP • Part of the structure of nucleic acids (DNA and RNA)
Disaccharides • AKA simple sugars • 2 monosaccharides joined by dehydration synthesis • EX – sucrose (table sugar) is glucose and fructose
Polysaccharides • AKA complex carbohydrates • Contain tens or hundreds of monosaccharides • Can be broken down by hydrolysis • Main polysaccharide in the human body is glycogen
Glycogen • Made entirely of glucose molecules joined in branching chains • Stored in the Liver and Skeletal Muscles • Can be broken down when energy demands in the body are high
Lipids (Fats) • Made of Carbon, Hydrogen and Oxygen • Proportion of Oxygen is usually lower than in carbohydrates • Not as many polar bonds so they are not soluble in water • Include triglycerides, phospholipids, steroids, fatty acids and fat soluble vitamins (A, D, E and K)
Triglycerides • Most plentiful lipid in the body • Most highly concentrated form of energy • Adipose Tissue = Fat Tissue • Excess dietary carbohydrates, fats and protein are all deposited in adipose tissue
Glycerol – backbone of a triglyceride • Fatty Acid Chain – 3 connect to the glycerol
Fatty Acids • Saturated – contain only single covalent bonds between carbons • Unsaturated contain 1 or more double bonds between carbons • Monounsaturated – only 1 double bond • Polyunsaturated – more than 1 double bond
Double bonds cause the carbon chains to bend in an unsaturated fat
Phospholipids • The lipids you find in the cell membrane • Glycerol with 2 fatty acid chains and a phosphate group
Steroids • Rings of 4 carbons rather than chains • Cholesterol is the steroid from which other steroids are made • Examples: esterdiol, testosterone, cortisol and Vitamin D
Protein • Large molecules containing Carbon, Hydrogen, Oxygen, Nitrogen and sometimes Sulfur • Building Blocks are Amino Acids
Amino Group • --NH2
Carboxyl Group • --COOH
“R” Group (Radical Group) • 20 different side chains that determine which amino acid the molecule will be
Peptide • The union of 2 or more amino acids • Dipeptide = 2 aa • Tripeptide = 3 aa • Polypeptide = lots of aa
Peptide Bond • The bond formed between 2 amino acids
Protein • A protein is a polypeptide that can contain as few as 50 aa’s or as many as 2000 aa’s • The variation in the number and sequence of aa’s produces a different protein
Protein Structures • Primary • Secondary • Tertiary • Quaternary
Denaturation • If temperature, pH or ion concentration is altered, a protein may unravel and lose it shape • If a protein changes shape (is denatured) it is no longer functional because… • SHAPE DETERMINES FUNCTION!
Enzymes • Protein Catalyst • A substance that can speed up a chemical reaction without themselves being altered • Names of catalysts generally end in -ase • Ex. Kinase, dehydrogenase, amylase
Properties of Enzymes • Specificity – each particular enzyme catalyze a particular chemical reaction • Lock and Key • Efficiency – under optimal conditions, enzymes can catalyze reactions at rates millions of times that of an uncatalyzed reation. • Control – rate of synthesis is under the control of the cell’s genes
Enzyme Vocab • Substrate – the molecule on which the enzyme acts • Products – molecule(s) produced by the reaction • Cofactor/Coenzyme – a nonprotein substance that some enzymes require to operate properly • Active Site – the particular spot on the enzyme molecule that catalyzes the reaction • Enzyme-Substrate Complex – a temporary compound formed when the enzyme and substrate bind
Review of Organic Compounds • Carbohydrates • Building blocks = monosaccharides • Lipids (Triglycerides) • Building Blocks = glycerol and fatty acids • Proteins • Building Blocks = amino acids