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Continued Leadership in the DOV Collaboration. By Nike Grange. DOV.
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Continued Leadership in the DOV Collaboration By Nike Grange
DOV Designed to develop a long-term plan by all Vaccine and Immunization stakeholders in order to scale up immunization programmes whilst maintaining a balance between activities that should lead to elimination of vaccine preventable diseases and those that will sustain routine immunization
Costs not included • Cost for research & development of new vaccines • Cost of scaling up seasonal influenza vaccination • Increased Surveillance • Increased CSO engagement • Current & additional technical agency support
Reasons for DOV • Cost-effectiveness of Immunization • Reduction in deaths • Reduction in Measles deaths by 74% • Reduction in Polio by 99% • Still sizable Gap in no of children unimmunised and under-immunised • Global disparities • Continuous emergence of new birth cohorts
Goals • World free from Polio • Meet global and regional disease elimination targets • Understand value of vaccines and demand imunzation as a right • Immunization programmes to have sustainable access to predictable funding, quality supply and innovative technologies
Benefits and Costs • 24-66 b No of deaths that cn be averted by reaching target immunization in 8 countries • $50-60 B Cost of scaling up routine immunization efforts & continue to provide accelerated disease control programs in 94 low and middle-income countries • $32 B Anticipated funding from Governments & GAVI Alliance. Funding from GAVI is dependent on donor $ country decisions • S18-28B Additional funding required
Costs estimates based on: • Vaccines and Supplies • Transportation & Cold Chain • HUMAN RESOURCES • Training • No clinical supervision-to improve quality of care • Record keeping, data generation, storage, retrieval & dissemination Social Mobilization/Communication Surveillance & Programme Management
R&D Goals • Operational & implementational research agenda • Basic research • New Vaccines • Platform vaccines & a research-based global regulatory agenda • New manufacturing technologies
Leadership Council • WHO • Bill and Melinda Gates • US National Institute of allergy & Infectious Diseases • Sabin Vaccine institute-Polio& Measles