Welcome to BIOL 252 Anatomy and Physiology

1. Welcome to BIOL 252 Anatomy and Physiology http://www.youtube.com/watch?v=ZRoSy1Hwouo

2. Welcome to BIOL 252 Anatomy and Physiology Dr. Gidi Shemer bishemer@email.unc.edu http://www.bio.unc.edu/courses/2009Fall/Biol252Sections456/ Office: Wilson G41 Office hours: Tue and Thur 02:00-04:00

3. Labs Wilson 111, 212 My office Wilson G41

4. Departmental Advising http://www.bio.unc.edu/Faculty/Shemer/ Available courses Research opportunities Choosing the right course Graduate school in Biology Career decisions Resources at UNC http://learningcenter.unc.edu// For example: tutoring (every TW 6-9, or by appointment) including BIOL252

5. Departmental Advising “Smart students take advantage of resources. Successful students seek help”

6. Anatomy : the study of structure Physiology : the study of function The lab will mainly deal with Anatomy Coordinated by Dr. Corey Johnson Self-work with 3D models Quizzes on blackboard BEFORE the lab

7. Marieb and Hoehn, third edition

8. Grading 25% x 3 exams = 75% lab exercises = 25% Lectures are important (respect your peers) No notes provided Use the ppt handouts Answer open questions THINK!!! Spoonfeeding- not on my watch

9. Blackboard • Announcements • Syllabus, schedule • Powerpoints • Assigned readings • Links • Grades

10. Optional Lab Manual: Recommended for those who know themselves to be kinesthetic learners. If coloring between the lines is useful to you and helps you remember lots of information, this manual is recommended. The author feels the manual is overpriced, so you will be able to “get by” without it. A more bare-bones version will be made available through blackboard at no cost. Bookstore only Bookstore only (arriving Friday)

11. Lab Info: • Lab is a co-requisite. Students not enrolled for a lab will be dropped from lecture enrollment. • Labs begin Monday, August 31 • A syllabus will appear on your lab blackboard site in the next week • You will likely have an assignment due on your first day of lab. Pay attention to the “announcements” section of you lab blackboard site.

12. Registration • Sign-up sheet available up front • Those with relevant needs have priority • major requirement – nursing, pharmacy, etc. • Otherwise: Seniors > Juniors > Sophomores • Being pre- (med, dental, vet, ophthalmology, etc.) does not constitute a priority

13. Physiology Homeostasis

14. Homeostasis how the varied components of living things adjust to maintain a constant internal environment that makes possible optimal functioning WB Cannon So we have a balanced state, but it is NOT static!! Homeostatic Imbalance = Diseases (e.g. diabetes)

15. Anatomy Gross Anatomy- study of structures visible to the naked eye Microscopic Anatomy- study of structures visible ONLY with a microscope

16. Levels of organization Cellular Chemical Tissue Organismal Organ Organ system

18. Planes of the Body Frontal plane Sagittal plane mid/ para Transverse plane

19. Body Cavities

21. Covering and Lining Membranes Cutaneous Membrane (covering the surface) Mucous Membranes (open to the exterior)

22. Covering and Lining Membranes of the Ventral Body Cavity Serous Membranes (moist)

23. Covering and Lining Membranes of the Ventral Body Cavity

24. Levels of organization Cellular Chemical Tissue Organismal Organ Organ system

25. Support Protect Control Movement

26. Different Tissues can be Found in One Organ

27. Epithelial Tissue 1) Covering and lining epithelium 2) Glandular epithelium Functions 1) Protection (e.g. skin) 2) Sensory Reception (e.g. skin) 3) Absorption (e.g. intestine) 4) Secretion and Filtration (e.g. kidney) e.g. = exempli gratia, "for the sake of an example"

28. Epithelial Cells are Closely Bound Together

29. Epithelial Cells are Closely Bound Together

30. Epithelial Cells are Polarized Apical Basal Apical-towards the lumen/surface Basal- towards underlying cells Lateral-contacting other epithelial cells

31. Characteristics of Epithelial Cells Polarized Closely Bound Together Avascular but Innervated High Regenerative Capacity

32. Classification of Epithelia squamous cuboidal columnar simple stratified

37. Epithelial Tissue 1) Covering and lining epithelium 2) Glandular epithelium

38. Glandular Epithelia A Gland: cell/s that make and secrete products. Endocrine Glands: secreting internally, to the extracellular space Exocrine Glands: secreting externally, to the body surface or body cavities

39. Endocrine Glands: secreting internally, to the extracellular space (hormones)

40. Exocrine Glands: secreting externally, to the body surface or body cavities A goblet cell, secreting mucin

41. Modes of Secretion Holocrine Merocrine

42. The connective Tissue

43. Connective Tissue Functions Support Protection Insulation Transport

44. Connective Tissue Cells + Extracellular Matrix (ECM) http://fulton.edzone.net/

45. Extracellular Matrix (ECM) Ground Substance + Fibers

46. Ground Substance Tissue fluid Adhesion proteins Proteoglycans (GAGs + a core proteins)

47. Extracellular Matrix (ECM) Ground Substance + Fibers Tendon Bone

48. Fibers of connective tissues Collagen fibers Reticular fibers Elastic fibers

49. Defect in collagen assembly

50. Connective Tissue Cells + ECM = ground substance+ fibers http://fulton.edzone.net/