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HK2. PFK1. ACLY. PDK1. IDH1. GLS1. MCT1/4. MPC. CTP. ME1. mIDH1. FH. SDH. ASCT2. Glucose. GLUT1/4. Complex Sugar Synthesis. HIF1 α. Myc. 13 C. LKB1. PTEN. Glucose. VHL. RTK. Glucose-6-Phosphate. LKB1. Pentose Phosphate Pathway. PI3K/ AKT. NADPH. HIF1 α.
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HK2 PFK1 ACLY PDK1 IDH1 GLS1 MCT1/4 MPC CTP ME1 mIDH1 FH SDH ASCT2 Glucose GLUT1/4 Complex Sugar Synthesis HIF1α Myc 13C LKB1 PTEN Glucose VHL RTK Glucose-6-Phosphate LKB1 Pentose Phosphate Pathway PI3K/AKT NADPH HIF1α Fructose-6-Phosphate AMPK Lipid Synthesis Nucleotide Synthesis Fructose-1,6-bisphosphate p53 AMPK Glyceraldehyde-3-phosphate PI3K/AKT Amino-Acid Synthesis 3-Phosphoglycerate Acetyl-CoA Phosphoenolpyruvate p53 Serine Biosynthesis NAD PKM2 RTK PC NADH Myc Serine 13C Lactate Lactate Pyruvate Myc Alanine HIF1α Glycine HIF1α Myc NADPH Citrate 13C LDHa Pyruvate Isocitrate PDH Acetyl-CoA α-Ketoglutarate Citrate Aspartate Oxaloacetate IDH2 2-Hydroxyglutarate α-Keto- glutarate Malate Malate Glutamate TCA Cycle Glutaminolysis Myc Succinate Fumarate Proline Glutamine Glutamine 13C