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The Effects of Hazardous Materials on the Body. What risks?. Toxicity: the ability of a substance to cause dangerous effects Factors relating to toxicity: Dose Length of exposure Route(s) of entry. Routes of Entry. Inhalation: Breathing in of contaminant
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What risks? • Toxicity: • the ability of a substance to cause dangerous effects • Factors relating to toxicity: • Dose • Length of exposure • Route(s) of entry
Routes of Entry • Inhalation: • Breathing in of contaminant • Can affect soft tissues of respiratory system • Lung damage • Lower breathing capacity • Trigger onset of chronic disease (ie; cancer) • Can become systemic (throughout body) • Passes through lung tissue into blood stream
Inhalation Example 1 - Asbestos • Fibres act like ‘fish hooks’ on lung tissue • Never go away • Trigger lung cancer (80% fatality rate)
Inhalation Example 2 - Mycosis • Fungal growth in lung tissue • Inhibits respiration • Toxic by-product causing tissue damage
Routes of Entry • Absorption: • Contamination by contact • Can cause rashes, burns, infection, ect • Can become systemic
Absorption Example: Mercury • Absorbed in tiny droplets through skin tissue • Travels through body and destroys nervous (brain) tissue
Routes of Entry • Ingestion: • Swallowing or eating • Can be direct contact (swallowing on its own) • Can be indirect (ingesting contaminated food/drink)
Ingestion Example: Lead • Ingestion damages many body systems and organs • Can cause pain, developmental disorders, seizures and death • Contaminant in soil and water (contaminated veggies and fish)
Common Ways Chemicals Enter Body • Air: • Mist, dust, gas, vapours • Usually enter indirectly (ie; dirty hands, air currents) • Can be odourless/colourless and undetected • Liquids: • Improper handling • Dust absorbed by sweat or by moist eye surface • Transfer across placenta (pregnancy)
Exposure • 2 types: Acute: • Short term • Rapid effects Chronic: • Repeated exposure • Delayed effects