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Building Blocks of Organic Compounds. Madison Southern High School Biology Unit - Biochemistry. What is an organic compound?. Biochemistry What are living things made of?. C, H, N, O, P, S 98% of living matter Mn, Fe, Co, Cu, Zn electron carriers
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Building Blocks of Organic Compounds Madison Southern High School Biology Unit - Biochemistry
Biochemistry What are living things made of? • C, H, N, O, P, S 98% of living matter • Mn, Fe, Co, Cu, Zn electron carriers • Na, Mg, Cl, K, Ca only as ions • trace elements
Why These 16? • Unique chemical properties • C, N, O: form multiple strong bonds • P: part of ATP/DNA; bonds store energy
What is a polymer? • Most macromolecules are polymers • monomer • polymer • macromolecule
4 types of organic compounds • Carbohydrates • Lipids • Proteins • Nucleic Acids Essential for all living things
Monosaccharides Draw the structures of the three Monosaccharides. The three structures are isomers. What does that mean? Bonds – Black Carbon – RedHydrogen – BlueOxygen – Green
Monosaccharides GLUCOSE GALACTOSE Bonds – Black Carbon – RedHydrogen – BlueOxygen – Green
Carbohydrates • contain C, H, O • Important because they contain a great deal of energy which is stored in the bonds • called sugar or saccharide With energy from light, plants can build sugars from carbon dioxide and water.
3 Types of Carbohydrates • Monosaccharide • Disaccharide • Polysaccharide
3 Types of Carbohydrates • Monosaccharide – monomer • Single sugar made of 5 or 6 carbon atoms • Examples of Monosaccharides
2. Disaccharides Two sugar molecule • Examples of Disaccharides
How to make a Disaccharide Condensation or Dehydration synthesis reactions
Condensation or Dehydration Synthesis of a Disaccharide
How to digest or break down a disaccharide? • Hydrolysis Reaction • Must use or split a water molecule
3. Polysaccharides • 3) Polysaccharide – Polymer • Made by condensation reactions- Bonding Many simple sugar molecules together to form the macromolecules • Can be made of 1000s of monosaccharides
Examples of Polysaccharides • Humans cannot digest these polysaccharides Structural Polymers
3 Types of Carbohydrates …MORE Examples of Polysaccharides Storage Polymers
How do digest or break down Polysaccharides?By Hydrolysis Reactions • Polysaccharides are digested by hydrolysis reactions just like disaccharides. • Must use a water molecule for each bond broken between simple sugar molecules.
Examples of Carbohydrates The small black granules (dots) are glycogen.
Lipids-Fats, Oils,Sterols LOOK in your book on page58 Monomers of Lipids Glycerol – C3H5(OH)3 Saturated Fatty Acid – C5H11COOH Unsaturated Fatty Acid – C5H9COOH Bonds – Black Carbon – RedHydrogen – BlueOxygen – Green
Lipids • Fatty Acid – monomer • COOH carboxyl group at one end (polar) • Attracted to water (hydrophilic) • Hydrocarbon end (nonpolar) • tends not to interact with water (hydrophobic)
Lipids What is the difference between saturated and unsaturated fats? Solid at room temperature - animal fats (bacon, lard, butter) Liquids at room temperature - olive oil, corn oil.
Saturated Fats • At room temperature, saturated fats are usually solid. • Source: primarily in animal products including beef, lamb, pork and chicken, egg yolk, dairy fats of cream, milk, cheese, butter; coconut and palm oil; non-dairy creams because they contain coconut oil • Consumption of saturated fats has been linked with risk of coronary heart disease: • sources of saturated fat are full of cholesterol(except coconut and palm oil) • diet high in saturated fat facilitates cholesterol synthesis by the liver (including coconut and palm oil)
At room temperature, unsaturated fats are usually liquid. Monounsaturated Sources: olive, peanut, canola, rape oil, almonds, avocado Polyunsaturated Sources: sunflower, soybean, corn, and safflower oil, fish oil, walnuts, sesame seeds, pumpkin seeds, tofu, lard Unsaturated Fats
Trans-unsaturated fatty acids (TFA) • TFA are product of hydrogenation which increases the saturation of fatty acids within oils and converts natural cis to trans configuration • Hydrogenation= industrial process that chemically transforms a low melting point oil into a solid fat with a higher melting point to enhance product taste, stability and shelf life. • Found in commercially fried foods(French fries, popcorn), commercial baked goods and snacks (cakes, cookies, biscuits), margarine, and cheapvegetableshortenings (not in e.g. Flora, Rama). • Trans-fatty acids have many adverse metabolic effects including elevation of LDL cholesterol, triglycerides, reduction in HDL cholesterol, and adverse effects on endothelial function, inflammatory markers, and probably insulin resistance.
Types of LipidsPhospholipids • Lipids that are found in a membrane or barrier of a cell or cell structures - Used mainly for structure
Types of LipidsTriglycerides • Energy storage - High energy molecules (twice the energy found in glucose) • Found in cells – cushions and insulates body and nerves • Made from 1 glycerol + 3 fatty acid tails = triglyceride
Types of LipidsWaxes • Forms a barrier for protection Ear wax Waxy leaves
Types of LipidsSteroids • Ring structures (no fatty acids) • Animal hormones – testosterone, estrogen, progesterone
Proteins • Polymers (polypeptides) are formed from 20 different monomers (amino acids) • Structure of an amino acid
Amino Acids R groups (shaded white) determine the chemical properties of an amino acid
Making a polypeptide chain • peptide bonds form between COOH and NH2
Proteins Amino acids build two types of proteins 1) Structural: This type is used in building structures in an organism 2) Chemical: This type gets involved in chemical reactions. Antibodies and enzymes perform chemical chores.
Nucleic Acids • Store important information in the cell • Consist of nucleotides (monomer) • Nucleotide • 5 carbon sugar • Phosphate group • Nitrogen base • Adenine • Cytosine • Thymine • Guanine
Nucleic Acids DNA and RNA are polymers, composed of thousands of monomers (nucleotides)
Nucleic Acids DNA contains information essential for cell activities.
Nucleic Acids RNA stores and transfers information necessary for making proteins.
ATP: Adenosine Triphosphate A nucleotide
ATP: Adenosine Triphosphate A nucleotide • Primary energy source for the cell • Key to ATP’s usefulness 3 phosphate groups Let’s Read ATP, Your Rechargeable Battery
Review Carbohydrates What is the polymer? Polysaccharide Cellulose Starch Glycogen What is the monomer? Monosaccharide