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Cardiovascular System. Size of Heart. Average Size of Heart 14 cm long 9 cm wide. Location of Heart. posterior to sternum medial to lungs anterior to vertebral column base lies beneath 2 nd rib apex at 5 th intercostal space lies upon diaphragm. Coverings of Heart .
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Size of Heart • Average Size of Heart • 14 cm long • 9 cm wide
Location of Heart • posterior to sternum • medial to lungs • anterior to vertebral column • base lies beneath 2nd rib • apex at 5th intercostal space • lies upon diaphragm
Heart Chambers • Right Atrium • receives blood from • inferior vena cava • superior vena cava • coronary sinus • Left Atrium • receives blood from pulmonary veins • Right Ventricle • receives blood from right atrium • Left Ventricle • receives blood from left atrium
Heart Valves Tricuspid Valve Pulmonary and Aortic Valve
Skeleton of Heart • fibrous rings to which the heart valves are attached
Heart Actions Atrial Diastole/Ventricular Systole Atrial Systole/Ventricular Diastole
Cardiac Cycle • Atrial Systole/Ventricular Diastole • blood flows passively into ventricles • remaining 30% of blood pushed into ventricles • A-V valves open/semilunar valves close • ventricles relaxed • ventricular pressure increases
Cardiac Cycle • Ventricular Systole/Atrial diastole • A-V valves close • chordae tendinae prevent cusps of valves from bulging too far into atria • atria relaxed • blood flows into atria • ventricular pressure increases and opens semilunar valves • blood flows into pulmonary trunk and aorta
Heart Sounds • Lubb • first heart sound • occurs during ventricular systole • A-V valves closing • Dupp • second heart sound • occurs during ventricular diastole • pulmonary and aortic semilunar valves closing Murmur – abnormal heart sound
Cardiac Muscle Fibers • Cardiac muscle fibers form a functional syncytium • group of cells that function as a unit • atrial syncytium • ventricular syncytium
Electrocardiogram • recording of electrical changes that occur in the myocardium • used to assess heart’s ability to conduct impulses P wave – atrial depolarization QRS wave – ventricular depolarization T wave – ventricular repolarization
Electrocardiogram A prolonged QRS complex may result from damage to the A-V bundle fibers
Regulation of Cardiac Cycle Autonomic nerve impulses alter the activities of the S-A and A-V nodes
Regulation of Cardiac Cycle Additional Factors that Influence HR • physical exercise • body temperature • concentration of various ions • potassium • calcium • parasympathetic impulses decrease heart action • sympathetic impulses increase heart action • cardiac center regulates autonomic impulses to the heart
Blood Vessels • arteries • carry blood away from ventricles of heart • arterioles • receive blood from arteries • carry blood to capillaries • capillaries • sites of exchange of substances between blood and body cells • venules • receive blood from capillaries • veins • carry blood toward ventricle of heart
Arteries and Arterioles • Arterioles • thinner wall than artery • endothelial lining • some smooth muscle tissue • small amount of connective tissue • helps control blood flow into a capillary • Artery • thick strong wall • endothelial lining • middle layer of smooth muscle and elastic tissue • outer layer of connective tissue • carries blood under relatively high pressure
Arteriole • smallest arterioles only have a few smooth muscle fibers • capillaries lack muscle fibers
Metarteriole connects arteriole directly to venule
Capillaries • smallest diameter blood vessels • extensions of inner lining of arterioles • walls are endothelium only • semipermeable • sinusoids – leaky capillaries
Regulation of Capillary Blood Flow • Precapillary sphincters • may close a capillary • respond to needs of the cells • low oxygen and nutrients cause sphincter to relax
Exchange in the Capillaries • water and other substances leave capillaries because of net outward pressure at the capillaries’ arteriolar ends • water enters capillaries’ venular ends because of a net inward pressure • substances move in and out along the length of the capillaries according to their respective concentration gradients
Venules and Veins • Venule • thinner wall than arteriole • less smooth muscle and elastic tissue than arteriole • Vein • thinner wall than artery • three layers to wall but middle layer is poorly developed • some have flaplike valves • carries blood under relatively low pressure • serves as blood reservoir
Arterial Blood Pressure Blood Pressure – force the blood exerts against the inner walls of the blood vessels • Arterial Blood Pressure • rises when ventricles contract • falls when ventricles relax • systolic pressure – maximum pressure • diastolic pressure – minimum pressure
Pulse • alternate expanding and recoiling of the arterial wall that can be felt
Control of Blood Pressure Controlling cardiac output and peripheral resistance regulates blood pressure
Control of Blood Pressure If blood pressure rises, baroreceptors initiate the cardioinhibitory reflex, which lowers the blood pressure
Control of Blood Pressure Dilating arterioles helps regulate blood pressure