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Cancer and mitosis case study

Cancer and mitosis case study. Spring 2014. Created by K.D. Lewis Robert B. Glenn High School. Biology objectives 1.2.2. Outline the cell cycle: Growth 1, Synthesis, Growth 2, Mitosis, and Cytokinesis

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Cancer and mitosis case study

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  1. Cancer and mitosis case study Spring 2014 Created by K.D. Lewis Robert B. Glenn High School

  2. Biology objectives 1.2.2 • Outline the cell cycle: Growth 1, Synthesis, Growth 2, Mitosis, and Cytokinesis • Recognize that mitosis is apart of ASEXUAL reproduction and meiosis is a part of sexual reproduction • Organize diagrams of mitotic phases and describe what is occurring throughout the process. • Compare mitosis to meiosis • Understand that tumors (and cancer) result as an error in mitosis

  3. Error in mitosis • Tumors result as an error in Mitosis. • Cells divide continually without stopping. This results in a tumor. • Tumors are simply a cluster of cells. • Tumors can be malignant (cancerous) or benign {PRONOUNCED ‘BEE-nine’} (non-cancerous) • Cells are supposed to die. This is called apoptosis. If cells fail to die, tumors form.

  4. Warning: • The following slides contain graphic images of people suffering from various cancers. • Not all tumors are malignant • Please exhibit respect, maturity, and empathy when viewing these images.

  5. Examples of tumors • Keep in mind that your entire body is made of cells. A tumor is a cluster of cells that have abnormal growth. • A tumor can form ANYWHERE

  6. Examples of tumors Various Facial tumors of the nose, mouth, and eye Cell Theory Review: ALL LIVING THINGS are made of Cells! A tumor can form ANYWHERE! TUMORS = CELLS GONE WRONG!

  7. Examples of tumors

  8. Instructions for the assignment • This assignment is completed INDIVIDUALLY • This assignment will also count towards your FINAL PORTFOLIO PROJECT. So SAVE THIS!!! • It is your responsibility to remain on task, and turn this assignment in ON TIME. • Each day that it is late, 10 points will be deducted. • This is a research project, and you must site ALL SOURCES in a reference page. • It must be completed electronically, and submitted in Edmodo by March 10, 2014

  9. Assignment: Part IEssential Vocabulary • CELL CYCLE • Interphase • Mitosis • Cytokinesis • Prophase • Metaphase • Anaphase • Telophase • Tumor • Cancer • Malignant • Benign • Abnormal • Metastasis • Sister chromatids • Centromere • Centriole • Spindle • Parent cell • Daughter cell • apoptosis In your presentation: Define the following terms in complete sentences

  10. Assignment: Part II“The Cell Cycle” • Define all parts of the Cell Cycle. • Locate pictures for EACH phase of the cell cycle • Explain why apoptosis is important. • Explain how tumors form as a result of an error in Mitosis

  11. Assignment: Part III(Medical Article Analysis) • You must choose one (1) of the following articles, and provide a detailed (1 page) summary, written in your own words! • Article #1: http://www.nature.com/scitable/topicpage/cell-division-and-cancer-14046590 • Article #2: http://www.biologycorner.com/worksheets/articles/cancer.html • Article #3: http://www.brighthub.com/science/genetics/articles/33788.aspx

  12. Assignment IV:Cancer Research • Research one of the following types of cancer: ovarian, prostate, throat, cervical, tongue cancer, cheek cancer, colon cancer, rectal cancer, nasal cavity, salivary gland cancer • Research symptoms • Provide treatment information • Provide prevention and early detection methods (if applicable). • Provide your rationale(reason) for why you chose to research this type of cancer. • Photos must be included in your presentation

  13. Assignment V: Case Study and patient Treatment • Read through the mock medical charts of each patient. • Research the possible modes of treatment (next slide), and decide which is best for each of the patients. • Consider medical costs, insurance, and health risks. • What are the side effects of your chosen treatment? • Reviewing #1-4, tell how you would treat EACH patient.

  14. SomePossible treatment options 1. Surgery: to remove the tumor 2. Chemotherapy: use of medicine or drugs to treat cancer. “Chem” means chemical. 3. Radiation: much like x-rays. This is a painless procedure that uses rays to kill the abnormal cell’s DNA. This could also kill normal cells. 4. Homeopathic (natural) remedies: some say these methods don’t CURE cancer, but TREAT the symptoms: change in diet, exercise, cutting carbs, certain vitamins 5. Stem cell treatment: after cancerous cells (and some normal cells) are destroyed using chemo and radiation, doctors use stem cells to repair ANY damaged cells.

  15. FYI: Stages of Cancer

  16. Patient #1 • Name: Carson Jones • Male, 56 • Cancer type: Prostate • Stage: 2 • Profession: Pediatrician. Graduate of Wake Forest, UNC-CH. • Family: one wife, 3 adult daughters, 2 grandchildren. • Additional info: Previously had surgery to remove the tumor. The tumor came back the following year.

  17. Patient #2 • Name: Joe Berry • Male, age 81 • Cancer type: Lung Cancer • Stage: 4 • Profession: retired • Family: wife, 5 adult children, 10 grand children • Additional info: Patient has undergone 2 rounds of chemotherapy and radiation with minimal success.

  18. Patient #3 • Name: Maria Valdez-Aguilar • Cancer type: Ovarian • Stage: 3 • Profession: • Family: husband (Deceased. Fatally wounded in Iraq). One son. Unable to have more children due to the location and Metastasisof her tumor. • Additional info: Patient was advised to have a hysterectomy (removal of uterus and ovaries) to remove the source of cancer. Patient refused. Now the cancer has begun to spread (metastasize) to her bladder.

  19. What exactly do I turn in? • Assignment I: Essential Vocabulary (all terms defined) • Assignment II: All parts of the cell cycle defined (IPMATC), which pictures of each phase • Assignment III: Medical Journal Article Analysis (1-page summary written in your own words) • Assignment IV: Cancer Research • Assignment V: Patient Analysis & Treatment • Reference Page: all sources listed

  20. Helpful links • http://www.cancer.gov/cancertopics/factsheet/Therapy/radiation • http://www.cancertutor.com/ • http://articles.mercola.com/sites/articles/archive/2013/08/03/natural-cancer-treatment.aspx • http://www.cancer.gov/cancertopics/factsheet/detection/staging • http://www.abpischools.org.uk/page/modules/celldiv_cancer/.cfm?coSiteNavigation_allTopic=1 • http://www.cancer.org/treatment/treatmentsandsideeffects/treatmenttypes/bonemarrowandperipheralbloodstemcelltransplant/stem-cell-transplant-types-of-transplant

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