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QU: Why do we breathe? **Need book the rest of the Unit** *Final Review is online!!* OBJ: S.M. Q’s, Types of energy and uses, Over Test. Friday December 14 th 2012. “Cockroaches can live for 9 days after their head has been cut off.”. QU: What is the word equation for cellular respiration?
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QU: Why do we breathe? **Need book the rest of the Unit** *Final Review is online!!* • OBJ: S.M. Q’s, Types of energy and uses, Over Test Friday December 14th 2012 “Cockroaches can live for 9 days after their head has been cut off.”
QU: What is the word equation for cellular respiration? **Turn in Energy Homework to HW Bin** *CR Project Due at the End of the Hour WedNesday* • OBJ: C.R. Notes and C.R. Project “The warmest temperature ever recorded on Antarctica was 3 degrees F.” Monday December 17th 2012
Cellular Respiration Who? Why? Where? What?
In what organisms does cellular respiration take place?(WHO?)
Plants - Autotrophs: • self-producers. • Animals - Heterotrophs: • consumers. Plants and Animals…
We eat complex foods with large molecules. • These foods are full of energy BUT our body is not prepared to use the energy in that state. • We have to change it…… WHY?
Solution: Our body digests macromolecules into their monomers. • Main focus for this class: carbohydrates into glucose. • Then cellular respiration retrieves the glucose and takes over!! WHY? (cont.)
Cellular respiration’s main function • Turn glucose into useable ATP • 38 ATP per Glucose molecule • Also forms carbon dioxide and water C6H12O6 + 6O2 6CO2 + 6H2O + energy (Glucose) (ATP) WHY? (cont.)
Cellular Respiration occurs in the… • Cytoplasm • Glycolysis---Cytosol (Cytoplasm) • Mitochondria • Krebs Cycle—Mitochondrial Matrix • Electron Transport Chain/ATP Synthase---Inner Mitochondrial Membrane WHERE?
Inner membrane space Matrix Cristae Outer membrane Inner membrane WHERE? (cont.)
Cellular Respiration: • catabolic, exergonic, oxygen (O2)requiring process that uses energyto extract energy (ATP) from macromolecules (glucose). • Catabolic: Rxn that breaks molecules down • Makes CO2 and H2O as well as energy (ATP) C6H12O6 + 6O2 6CO2 + 6H2O + energy (Glucose) (ATP) WHAT?
Adenosine Tri-Phospate: • Made of three things • 1.) Ribose (sugar) • 2.) Adenosine (base) • 3.) Three phosphates • Key to the activity of ATP AMP, ADP, ATP
ATP works by losing the endmost phosphate group when instructed to do so by an enzyme. • As the molecule goes from ATP to ADP to AMP it loses a phosphate. • With each lost phosphate more energy is released • This reaction releases a lot of energy, which the organism can then use to build proteins, contact muscles, etc AMP, ADP, ATP
ATP ADP AMP ATP to ADP To ADP releases energy
HOW: Steps of Cellular RespirationGlycolysis and Krebs Cycleand Substrate Level Phosphorylation
QU: How is energy released from the ATP? *CR Project Due Weds. at the end of the hour* Absent yesterday? Turn in your HW from Friday • OBJ: C.R. Notes and C.R. Project “The warmest temperature ever recorded on Antarctica was 3 degrees F.” Tuesday December 18th 2012
Cellular Respiration is broken into three main parts. • 1.) Glycolysis: splits sugar (glucose) • 2.) Krebs Cycle (Citric Acid Cycle): Extracts the energy from glucose • 3.) Electron Transport Chain/ATP Synthase: Turns the energy into ATP for the body to use **In total makes 38 ATP** WHAT? (cont.)
Occurs in thecytoplasm just outside of mitochondria. • Two phases: A. Energy investment phase -Put energy in B. Energy yielding phase -Get energy out Glycolysis
Glucose (6C) C-C-C-C-C-C 2ATP 2 ATP - used 0 ATP - produced 0 NADH - produced 2P 2ADP + C-C-C C-C-C Glyceraldehyde phosphate (2 - 3C) (G3P or GAP) • Energy Investment Phase: must put in 2 molecules of ATP to start Cellular Respiration Glycolysis: Step 1
Glyceraldehyde phosphate (2 - 3C) GAP GAP C-C-C C-C-C 4ADP + 4P 0 ATP - used 4 ATP - produced 2 NADH - produced 4ATP C-C-C C-C-C (PYR) (PYR) Pyruvate(2 - 3C) • Energy Yielding Phase: Rewarded for your investment by 4 ATP molecules Glycolysis: Step 2
Total Net Yield: 2 - 3C-Pyruvate (PYR) 2 - ATP(You put in two ATP and made for so total you have is 2 ATP) 2 - NADH Glycolysis: The final picture
The 2 Pyruvates (PYR) (3 Carbons) lose one carbon each. • Now they each have only 2 carbons and are called Acetyl CoA (PYR) (PYR) C-C-C C-C-C C-C C-C Acetyl CoA Acetyl CoA “The In-between”
Mitochondrial Matrix • Location: Mitochondrial Matrix • Acetyl CoA (2C)bonds to Oxalacetic acid (4C - OAA)to make Citrate (6C). • It takes 2 turnsof the krebs cycle to oxidize1 glucosemolecule. • Oxidize: remove electrons for energy Krebs Cycle (Citric Acid Cycle)
Total net yield(2 turnsof krebs cycle) 1.2 - ATP (substrate-level phosphorylation) -Substrate-level phosphorylation: when phosphates are added directly to a molecule of ADP or AMP to make ATP 2. 6 – NADH 3. 2 - FADH2 4. 4 - CO2 Krebs Cycle (Citric Acid Cycle)
2 Acetyl CoA (2C) Citrate (6C) OAA (4C) Krebs Cycle 4 CO2 2 FADH2 6 NAD+ 2 FAD 6 NADH 2 ATP 2 ADP + P 2 x around = Krebs Cycle
Steps of Cellular RespirationElectron Transport Chain (ETC)and Oxidative Phosphorylation
QU: • OBJ: C.R. Notes and Project “In 1845 Boston had an ordinance banning bathing unless you had a doctor's prescription.” *CR Project Due Today at the end of the hour* **CR Quiz on Friday** ***Journals Due Friday*** WedNesday December 19th 2012
Inner Mitochondrial Membrane • Location:inner mitochondrial membrane. • ETC and ATPSynthase(enzyme) make ATP. • ETCis a series of transport proteins that pump H+and electrons across the inner membrane to make ATP and Water. Electron Transport Chain (ETC)
All NADH and FADH2converted to ATP during this stage of cellular respiration. • Each NADH converts to 3 ATP. • Each FADH2 converts to 2 ATP. • Water is also made • Oxidative Phosphorylation: ATP synthesized from a proton gradient using electron pumps and ATP Synthase Electron Transport Chain (ETC)
Total ATP Yield 1. 04 ATP – Glycolysis and Krebs cycle 2. 34 ATP - ETC 38 ATP – TOTAL NET Yield ETC Video: http://www.youtube.com/watch?v=xbJ0nbzt5Kw&safety_mode=true&persist_safety_mode=1 Total ATP Yield…
QU: • OBJ: Cellular Respiration Webquest *Quiz tomorrow* **Bring Book the Rest of the Unit** *Test on the Weds. You Return* Thursday December 20th 2012
QU: What is the equation for Cellular Respiration? **Bring Book the Rest of the Unit** *Test on the Weds. You Return* • OBJ: C.R. Quiz, Over Energy, Review Friday December 21st 2012
QU: **Cellular Respiration Test on WedNesday** *Make-up Quiz today after school or tomorrow before school* • OBJ: Cellular Respiration Review Monday January 7th 2013
Syllabus • Word Search • Chapter 7 Section 1 Notes • Cellular Respiration Project • Cellular Respiration Webquest • Cellular Respiration and Fermentation Review • Cellular Respiration Graphic Organizer • Cellular Respiration Practice Quiz • Cellular Respiration Hand Written Notes Binder Organization: Ch 7
QU: What is one question you still have about cellular respiration? **Chapter Review Due tomorrow** *Binder Due Tomorrow* • OBJ: Cellular Respiration Review Tuesday January 8th 2013
QU: How did you study for this test? **Chapter Review to the HW Bin** *Binder to my Lab Table* • OBJ: Cellular Respiration Test WedNesday January 9th 2013