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Tony G.Waldrop Vice Chancellor Research and Economic Development

UNC-Chapel Hill and the NIH Roadmap. NIH ROADMAP. Tony G.Waldrop Vice Chancellor Research and Economic Development. NIH’s Roadmap Vision. Est. 2% of total NIH budget Primary funding source: “tax” on NIH institutes Emphasis: Attacking difficult problems Interdisciplinary collaboration

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Tony G.Waldrop Vice Chancellor Research and Economic Development

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  1. UNC-Chapel Hill and theNIH Roadmap NIH ROADMAP Tony G.Waldrop Vice Chancellor Research and Economic Development

  2. NIH’sRoadmap Vision • Est. 2% of total NIH budget • Primary funding source: “tax” on NIH institutes • Emphasis: • Attacking difficult problems • Interdisciplinary collaboration • Translation to clinic • Computation/informatics • Allied projects will make Roadmap much larger than its core funding Dr. Elias Zerhouni

  3. Themes New Pathways to Discovery • Building Blocks, Pathways, and Networks • Molecular Libraries and Imaging • Structural Biology • Bioinformatics and Computational Biology • Nanomedicine Research Teams of the Future • High-Risk Research • Interdisciplinary Research • Public Private Partnerships Re-engineering the Clinical Research Enterprise • Clinical Research Dorsal root ganglia neurons (Annette Markus)

  4. RoadmapPlanningat UNC • September, 2003: Dr. Zerhouni announces the Roadmap • January, 2004: 12-member Carolina Roadmap Task Force is convened • March, 2004: Task Force report recommends: • Create a campus-wide organization for Roadmap projects • Demonstrate administrative support • Appoint a Roadmap chair • Provide staff and resources

  5. UNC’sResponse • NIH Roadmap Executive Committee • Chair: Rudy Juliano, Professor of Pharmacology • Executive Committee members: • Kim Brouwer, Chair Pharmacotherapy, Pharmacy • Barbara Entwisle, Director, Carolina Population Center and Professor of Sociology • Michael Fried, Professor of Medicine and Director, Hepatology Division of Gastroenterology and Hepatology • Daniel Reed, Vice Chancellor for Information Technology and Director, Institute for Renaissance Computing • Rich Superfine, Professor of Physics • David Savitz, Chair of Epidemiology

  6. CampusSupport • Roadmap Committee will steer efforts to • Build research teams and partnerships at UNC • Liaise with NIH on Roadmap • Highlight interdisciplinary research (‘workshops’) • Facilitate development of proposals • A new staff position (Karen Stone) • Seed funding from VC for proposal development • Additional support from • Offices within Research and Economic Development • College of Arts and Sciences • Schools of Medicine, Dentistry, Public Health Freeze-dried, rehydrated platelets in a canine carotid artery. (Tom Fishcher)

  7. Action • The first round of Roadmap P20 RFAs yields multiple UNC proposals • REC meets with multiple Departments/Centers • VC’s “Workshops In Interdisciplinary Research” • Emerging Initiatives • Metabolomics— Steve Zeisel, others • Stem Cells & Transplantation—Jon Serody, others • Peridontal Disease—Steve Offenbacher, others • Biomedical Research Imaging Center—Etta Pisano, others • Pathways & Networks—Klaus Hahn others • Child abuse & physiological changes- Jonathan Kotch, others • Other projects?? Fluorescent video microscopy images of cell mitosis (Ted Salmon)

  8. SUCCESSES Roadmap Planning Grant or other Awards PI Theme Department/Center B. Popkin Obesity Population Center R. Rindfuss Land Use & Health Population Center B. Sartor Imaging Inflammation Medicine D. Reed/ Exploratory Genetics Computer Sci/ T. Magnuson Genetics G. Johnson Nanomedicine Pharmacology H. Guess Patient Outcomes Public Health

  9. WHAT NEXT? LOOKING FOR A FEW GOOD MEN/WOMEN 2. DARE TO DREAM BIG DREAMS

  10. Help the Roadmap at UNC Consider leading a Roadmap or Roadmap-Like proposal. Let us know about it!! 2. Help us to ‘penetrate’ the NIH. Are you on NIH Council? Study Section? Advisory Group? Let us know about it!!

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