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CTSA Consortiums: WESTRN

CTSA Consortiums: WESTRN. James F. Holmes, MD, MPH Professor, Department of EM UC Davis School of Medicine. CTSA Consortia. NIH wants CTSA consortia to develop Strategic Goal Committee 3: enhancing Consortium-Wide Collaborations August 26, 2011

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CTSA Consortiums: WESTRN

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  1. CTSA Consortiums: WESTRN • James F. Holmes, MD, MPH Professor, Department of EM UC Davis School of Medicine

  2. CTSA Consortia • NIH wants CTSA consortia to develop • Strategic Goal Committee 3: enhancing Consortium-Wide Collaborations • August 26, 2011 • https://www.ctsacentral.org/best%20practices/research%20networking • Implement research networking tools • Data available on people in each CTSA • Monitor collaborations • 15 regional consortia listed on NIH CTSA website • https://www.ctsacentral.org/regional-consortia

  3. West Coast Emergency Services Translational Research Network (WESTRN) • Oregon Health & Science University • Harborview/University of Washington • University of California at Davis • San Francisco General Hospital/UC San Francisco • Stanford University • Denver Health/University of Colorado • University of Utah • University of California at Irvine • University of Southern California • University of New Mexico

  4. WESTRN: Timeline • February 2008: 1st meeting of west coast CTSA leaders • May 2008: 1st meeting of EM investigators • 7 sites • Oct 2008: 2nd meeting of EM investigators • Developed process for protocol submission/approval • May 2009: 3rd meeting and planned project • July 2009: Protocol for 1st project • Feb 2010: Protocol for 2nd project • May 2012: 1st meeting of the 10 current sites

  5. WESTRN: Grants • Funded: • RWJ Foundation: PI Newgard • CTSC site grants for initial project: multiple sites • CDC R01: PI Newgard • UC Davis CTSA site grant for 2nd project: PI Nishijima • NIGMS F32: PI – Jody Vogel • Submitted: • NICHD R01 • NIGMS T32

  6. WESTRN: Projects • 1st Project: Link prehospital trauma data with outcomes data • 7 sites • Multiple projects within the database • 2nd Project: Variability of admission in patients with TBI • 8 sites • 3rd Project: Validation of Denver trauma MOF score • Part of a F32 training grant • 3 sites

  7. WESTRN: Publications • Abstracts: 12 at meetings from 2010 to 2013 • ACEP, SAEM, AAST, and American Heart Association – Resuscitation Symposium • Manuscripts: 7 • Initial project: 6 (JACS, Annals of EM, AEM, J Trauma, Prehospital EM Care) • 2nd project: 1 (Annals of EM)

  8. Thematic Special Interest GroupsConsortia • Self-developed consortia • 10 listed on NIH website: https://www.ctsacentral.org/tsig • Developing collaborations with existing networks, societies and organizations • Identifying specific research proposals for collaboration • Obtaining support from NIH Institutes and Centers, research institutions, and societies • Organizing workshops and meetings with support from NIH ICs, research institutions, and NIH conference grants • Meeting regularly in informal settings (teleconferences and at other pre-existing meetings) to share and collaborate

  9. ECTRC: National EM CTSA research network • National EM CTSA research network • https://www.ctsacentral.org/committee/emergency-care-researchers • May 2010 first meeting • Meetings each May at SAEM • Massive numbers of patients within network • Process, however, has been slow

  10. Conclusion • NIH wants consortiums among its CTSAs • Facilitate studies needing large numbers of subjects • Several existing consortia (see NIH website) • Regional and thematic • Challenges with large consortia

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