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Physiology of Respiratory System. Respiration. Pulmonary ventilation Breathing- air movement in and out of body External respiration Oxygen loading and Carbon dioxide loading Respiratory gas transport Gases transported via bloodstream Internal respiration
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Respiration • Pulmonary ventilation • Breathing- air movement in and out of body • External respiration • Oxygen loading and Carbon dioxide loading • Respiratory gas transport • Gases transported via bloodstream • Internal respiration • Exchange between capillaries and tissue cells
Breathing • Inspiration • Diaphragm flattens creates a vacuum pulling air into the lungs • Expiration • Muscles relax and push air out of the lungs
Respiratory Volumes and Capacities • Tidal Volume (TV)- volume of air moved into and out of the lungs each breath • Inspiratory reserve volume (IRV)- amount of air you can forcibly be taken in • Expiratory reserve volume (ERV)- amount of air that can be forcibly expelled
Respiratory Volumes and Capacities • Residual Volume- air that cannot be expelled from the lungs • Vital capacity (VC)- total amount of exchangeable air TV + IRV + ERV • Dead Space volume- the amount of air that doesn’t make it to the lungs in a breath
External Respiration • Gas exchange at the lungs • Oxygen into blood and CO2 removed from blood
Gas Transport in the Blood • Oxygen forms oxyhemoglobin with hemoglobin molecules • CO2 in transported via bicarbonate in plasma
Internal Respiration • Exchange of gases between blood and tissue cells • Oxygen unloaded and CO2 loaded
Hypoxia • Inadequate supply of oxygen to the body tissues • Causes skin to become cyanotic
Carbon Monoxide Poisoning • CO binds to the binding site that oxygen binds to on hemoglobin preventing gas transport of oxygen
Respiratory Terms • Eupnea- normal respiratory rate • Hyperpnea- increased respiratory rate (exercising) • Apnea- stopped breathing • Dyspnea- difficult breathing
Hyperventilation • Body’s reaction to increased levels of carbon dioxide or acids in blood