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CANCER DE TESTICULO

. SE CLASIFICA DESPUES DE UNA ORQUIECTOMIA RADICAL. pTX: NO PUEDE EVALUARSE TUMOR PRIMARIO pT0: NO HAY EVIDENCIA DE TUMOR PRIMARIO (Cicatriz Histol

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CANCER DE TESTICULO

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    1. CANCER DE TESTICULO DR JORGE RAUL ZIMERMAN PROFESOR ADJUNTO CATEDRA I CIRUGIA A / C MATERIA ONCOLOGIA JEFE DEPARTAMENTO DE ONCOLOGIA HOSPITAL DR. JOSÉ RAMÓN VIDAL

    2. SE CLASIFICA DESPUES DE UNA ORQUIECTOMIA RADICAL. pTX: NO PUEDE EVALUARSE TUMOR PRIMARIO pT0: NO HAY EVIDENCIA DE TUMOR PRIMARIO (Cicatriz Histológica en el Testículo) pTis: CARCINOMA in situ NEOPLASIA CELULAR INTRATUBULAR pT1: TUMOR LIMITADO AL TESTICULO Y EPIDIDIMO SIN INVASION LINFATICO / VASCULAR PUEDE INVADIR ALBUGINEA NO VAGINAL

    3. T. N. M pT2: TUMOR LIMITADO AL TESTICULO Y EPIDIDIMO CON INVASION LINFATICO VASCULAR- INVASION VAGINAL pT3: TUMOR INVADE CORDON ESPERMATICO CON O SIN INVASION LINFATICO VASCULAR pT4: TUMOR INVADE ESCROTO CON O SIN INVASION LINFATICO VASCULAR

    4. TNM NX: NO PUEDEN EVALUARSE GANGLIOS REGIONALES N0: NO HAY METASTASIS REGIONALES N1: MTTS 1 GANGLIO 2 CM O MENOS N2: MTTS 1 GANGLIO MAS DE 2 CM . MENOS DE 5 CM O GANGLIOS MULTIPLES NINGUNO MAS DE 5 CM N3: MTTS 1 GANGLIO DE MAS DE 5 CM

    5. TNM MX: NO SE PUEDE EVALUAR METASTASIS DISTANTES M0: NO HAY METASTASIS DISTANTES M1: METASTASIS A DISTANCIA M1a: METASTASIS PULMONAR O NO REGIONAL M1b: METASTASIS DISTANTES LINFATICAS Y PULMONARES

    6. BIBLIOGRAFIA Loehrer PJ, Lauer R, Roth BJ, et al.: Salvage therapy in recurrent germ cell cancer: ifosfamide and cisplatin plus either vinblastine or etoposide. Annals of Internal Medicine 109(7): 540-546, 1988. Loehrer PJ Sr, Gonin R, Nichols CR, et al.: Vinblastine plus ifosfamide plus cisplatin as initial salvage therapy in recurrent germ cell tumor. Journal of Clinical Oncology 16(7): 2500-2504, 1998. Motzer RJ, Cooper K, Geller NL, et al.: The role of ifosfamide plus cisplatin-based chemotherapy as salvage therapy for patients with refractory germ cell tumors. Cancer 66(12): 2476-2481, 1990. Broun ER, Nichols CR, Kneebone P, et al.: Long-term outcome of patients with relapsed and refractory germ cell tumors treated with high-dose chemotherapy and autologous bone marrow rescue. Annals of Internal Medicine 117(2): 124-128, 1992. Droz JP, Pico JL, Ghosn M, et al.: Long-term survivors after salvage high dose chemotherapy with bone marrow rescue in refractory germ cell cancer. European Journal of Cancer 27(7): 831-835, 1991. Cullen MH: Dose-response relationships in testicular cancer. European Journal of Cancer 27(7): 817-818, 1991. Motzer RJ, Mazumdar M, Bosl GJ, et al.: High-dose carboplatin, etoposide, and cyclophosphamide for patients with refractory germ cell tumors: treatment results and prognostic factors for survival and toxicity. Journal of Clinical Oncology 14(4): 1098-1105, 1996. Motzer RJ, Bosl GJ: High-dose chemotherapy for resistant germ cell tumors: recent advances and future directions. Journal of the National Cancer Institute 84(22): 1703-1709, 1992. Bhatia S, Abonour R, Porcu P, et al.: High-dose chemotherapy as initial salvage chemotherapy in patients with relapsed testicular cancer. Journal of Clinical Oncology 18(19): 3346-3351, 2000. Beyer J, Kramar A, Mandanas R, et al.: High-dose chemotherapy as salvage treatment in germ cell tumors: a multivariate analysis of prognostic variables. Journal of Clinical Oncology 14(10): 2638-2645, 1996. Murphy BR, Breeden ES, Donohue JP, et al.: Surgical salvage of chemorefractory germ cell tumors. Journal of Clinical Oncology 11(2): 324-329, 1993.

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