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Immunologia dei tumori

Immunologia dei tumori. T umor S pecific T ransplantation A ntigens e T umor A ssociated T ransplantation A ntigens. solo i tumori non immunogenici si sviluppano. si sviluppano i tumori che imparano a resistere al sistema immunitario. Due modelli. cellula bersaglio. MICA/MICB

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Immunologia dei tumori

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  1. Immunologia dei tumori

  2. Tumor Specific Transplantation Antigens e Tumor Associated Transplantation Antigens

  3. solo i tumori non immunogenici si sviluppano si sviluppano i tumori che imparano a resistere al sistema immunitario Due modelli

  4. cellula bersaglio MICA/MICB ULBP1,2,3,4 HLA-1 recettori inibitori recettori attivatori cellula NK Attivazione delle cellule NK Modificata da Backström et al. Scand. J. Immunol. 60:14-22, 2004

  5. FasL solubile IL-10 TGF- cellule immunitarie T T macrofagi dendritiche Fas cellula tumorale

  6. Treg complemento CCL22 IAPs CD46, CD55, CD59 membrane-bound Complement Regulatory Proteins (mCRPs) cellula tumorale

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