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SD-IAP 296

SD-IAP 296. Peter Vereš, PAO FN Trnava. SD-IAP 296. 85 ročný muž s nádorom vestibulárnej časti sliznice hornej pery veľkosti 3x3 cm, tuhšej konzistencie. SD-IAP 296. SD-IAP 296. Imunohistochemické vyšetrenia:

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SD-IAP 296

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  1. SD-IAP 296 Peter Vereš, PAO FN Trnava

  2. SD-IAP 296 • 85 ročný muž s nádorom vestibulárnej časti sliznice hornej pery veľkosti 3x3 cm, tuhšej konzistencie.

  3. SD-IAP 296

  4. SD-IAP 296 • Imunohistochemické vyšetrenia: • KL-1+, CEA ložiskovo+, EMA-, S-100 difúzne+, SMA ložiskovo+, p63 ložiskovo+, thyreoglobulín-, ER-, PR-, dezmín-, c-erbB-2-, Ki67-.

  5. KL-1

  6. SMA

  7. S-100

  8. CEA

  9. SD-IAP 296 • Diagnóza: • Polymorfný low-grade adenokarcinóm. • Malígny epiteliálny nádor charakteristický cytologickou uniformitou, morfologickou pestrosťou, infiltratívnym rastom a nízkym malígnym potenciálom ( WHO, Head and Neck Tumours, 2005).

  10. SD-IAP 296 • Dif.dg.: • Pleomorfný adenóm • Adenoidne cystický karcinóm

  11. SD-IAP 296 • Prognóza: • Veľmi dobrá • Lokálna recidíva sa udáva v rozpätí 9 až 17% • Regionálne metastázy v rozpätí 9 až 15%

  12. SD-IAP 296 • Literatúra: • WHO, Head and neck Tumours, 2005 • Richard J Zarbo M.D., D.M.D: Salivary Gland Neoplasia: A Review for the Practicing Pathologist, Mod Pathol 2002 • Mills SE, Garland TA, Allen MS Jr: Low-grade papillary adenocarcinoma of palatal salivary gland origin. Am J Surg Pathol. 1984 May • Gnepp DR, Chen JC, Warren C.: Polymorphous low-grade adenocarcinoma of minor salivary gland. An immunohistochemical and clinicopathologic study. Am J Surg Pathol. 1988 Jun

  13. SD-IAP 296 Ďakujem za pozornosť

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